Browsing by Author "Bilici, Ahmet"
Now showing items 1-20 of 88
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Advances in the management of unresectable or metastatic pancreatic neuroendocrine tumors: Chemotherapy, targeted therapy, hormonal treatment, and future directions
Bilici, Ahmet (Asian Pacific Organization for Cancer Prevention, 2015)Pancreatic neuroendocrine tumors (pNETs) are rare and heterogenous tumors and surgery to remove the primary tumor is the mainstay of treatment for resectable disease. However, curative surgery is often not feasible, because ... -
Are pretreatment inflammation-based prognostic scores useful in predicting the outcomes of patients with ALK-positive NSCLC?
Ölmez, Ömer Fatih; Bilici, Ahmet; Gürsoy, Pınar; Çubukçu, Erdem; Yıldız, Özcan; Sakın, Abdullah; Korkmaz, Taner; Çil, İbrahim; Çakar, Beyhan; Menekşe, Serkan; Demir, Tarık; Açıkgöz, Özgen; Hamdard, Jamshid (Elsevier Science, 2019)Background: Approximately 5% of all diagnosed non-small cell lung cancer (NSCLC) patients harbor a genetic rearrangement between the ALK and EML4 genes, representing a specific molecular and clinical subgroup (ALK+ NSCLC). ... -
Atezolizumab combined with chemotherapy in the first-line treatment of extensive-stage small cell lung cancer: A real-life data of the Turkish Oncology Group
Gürbüz, Mustafa; Kutlu, Yasin; Akkuş, Erman; Köksoy, Elif Berna; Köse, Naziyet; Öven, Bala Başak; Oyan Uluç, Başak; Demiray, Atike Gökçen; Erdem, Dilek; Demir, Bilgin; Turhal, Nazım Serdar; Üskent, Necdet; Akbaş, Sinem; Selçukbiricik, Fatih; İnal, Ali; Bilici, Ahmet; Ölmez, Ömer Fatih; Çabuk, Devrim; Ünal, Çağlar; Hizal, Mutlu; Şendur, Mehmet Ali Nahit; Korkmaz, Mustafa; Karadurmuş, Nuri; Ertürk, İsmail; Göksu, Sema Sezgin; Tatlı, Ali Murat; Güven, Deniz Can; Kılıçkap, Saadettin; Paksoy, Nail; Aydıner, Adnan; Yeşil Çınkır, Havva; Özkul, Özlem; Öztürk, Akın; Ballı, Sevinç; Kemal, Yasemin; Erdoğan, Atike Pınar; Er, Özlem; Yumuk, Perran Fulden; Demirkazık, Ahmet (Springer, 2022)Purpose Atezolizumab has been shown to be effective and safe in randomized trial in the first-line treatment of extensive-stage small cell lung cancer (SCLC). However, there are limited real-life data on atezolizumab. In ... -
Brain metastasis in a patient with malignant melanoma: Melanotic pattern
Dear Editor, A man aged 58 years who had been under follow up for malignant melanoma (MM) for six years, was admitted to the neurology outpatient clinic with symptoms of headache and loss of balance. He had had very severe ... -
Capecitabine-cisplatin versus 5-fluorouracil/leucovorin in combination with radiotherapy for adjuvant therapy of lymph node positive locally advanced gastric cancer
Öven Ustaalioğlu, Bala Başak; Bilici, Ahmet; Tilki, Metin; Sürmelioğlu, Ali; Erkol, Burçak; Figen, Metin; Uyar, Serab (Wolters Kluwer Medknow Publications, 2018)Aim of the Study: Although surgery is considered to be curative treatment, recurrence rates are high in gastric cancer. Adjuvant 5-fluorouracil (5-FU) based chemoradiotherapy has been shown to improve the prognosis. We ... -
Cetuximab-induced rash is associated with overall survival in patients with recurrent/metastatic squamous cell carcinoma of head and neck
Sezgin Göksu, Sema; Tatlı, Ali Murat; Geredeli, Çağlayan; Atçı, Mustafa; Beşen, Ali Ayberk; Mertsoylu, Hüseyin; Uysal, Mükremin; Özdoğan, Mustafa; Göktaş Aydın, Sabin; Bilici, Ahmet; Karaağaç, Mustafa; Artaç, Mehmet; Kaplan, Muhammet Ali; Ebinç, Senar; Coşkun, Hasan Şenol (Springer, 2021)Purpose In this study, we looked for whether treatment-induced rash predicts treatment efficacy in patients with recurrent/metastatic HNSCC treated with Cetuximab and chemotherapy. Methods Patients who were treated with ... -
The changing of serum vitamin B-12 and homocysteine levels after gastrectomy in patients with gastric cancer: do they associate with clinicopathological factors?
Bilici, Ahmet; Sonkaya, Alper; Ercan, Şerif; Ustaalioğlu, Bala Başak Öven; Şeker, Mesut; Aliustaoǧlu, Mehmet; Orçun, Asuman; Gümüş, Mahmut (Springer, 2015)After total (TG) or distal subtotal gastrectomy (DG), patients are at high risk of vitamin B-12 (vit-B-12) deficiency, which results in elevation of homocysteine levels. The changing of serum vit-B-12 and homocysteine ... -
Cisplatin plus paclitaxel and bevacizumab versus carboplatin plus paclitaxel and bevacizumab for the first-line treatment of metastatic or recurrent cervical cancer
İlhan, Yusuf; Tatlı, Ali Murat; Teker, Fatih; Önder, Arif Hakan; Köse, Fatih; Geredeli, Çağlayan; Karaağaç, Mustafa; Kaplan, Muhammet Ali; İnanç, Mevlüde; Göktaş Aydın, Sabin; Kargı, Ayşegül; Arak, Hacı; Özturk, Banu; Beşen, Ali Ayberk; Selvi, Oğuzhan; Korkmaz, Mustafa; Oruç, Zeynep; Bozkurt, Oktay; Bilici, Ahmet; Bayram, Selami; Dae, Shute Ailia; Özdoğan, Mustafa; Coşkun, Hasan Şenol; Sezgin Göksu, Sema (BMJ Publishing Group, 2022)OBJECTIVE: Cisplatin-paclitaxel and bevacizumab is a frequently used treatment regimen for metastatic or recurrent cervical cancer, and carboplatin-paclitaxel and bevacizumab are also among the recommended regimens. In ... -
The clinical and pathologic characteristics of 400 gastrointestinal stroinal tumor patients from Turkey: The final results of the Turkish Anatolian Society of Medical Oncology Multicenter Registery
Sevinç, Alper; Şeker, Mesut; Yıldız, Ramazan; Cihan, Şener; Kaplan, Mehmet Ali; Dane, Faysal; Karaca, Halit; Üyetürk, Ümmügül; Bilici, Ahmet; Özdemir, Nuriye; Uncu, Doğan; Salepçi, Tafian; Işıkdoğan, Abdurrahman; Benekli, Mustafa; Özkan, Metin; Gümüş, Mahmut; Öksüzoğlu, Berna (American Society of Clinical Oncology, 2014)… -
Clinical and pathologic features of patients with rare ovarian tumors: Multi-center review of 167 patients by the anatolian society of medical oncology
Bilici, Ahmet; İnanç, Mevlüde; Ulaş, Arife; Akman, Tülay; Şeker, Mehmet; Babacan Akgül, Nalan; İnal, Ali; Bal, Öznur; Koral, Lokman; Sevinç, Alper; Tufan, Gülnihal; Elkıran, Emin Tamer; Ustaalioğlu Öven, Bala Başak; Yavuzşen, Tuğba; Alkış, Necati; Özkan, Metin; Gümüş, Mahmut (Asian Pacific Organization for Cancer Prevention, 2013)Background: Non-epithelial malignant ovarian tumors and clear cell carcinomas, Brenner tumors, transitional cell tumors, and carcinoid tumors of the ovary are rare ovarian tumors (ROTs). In this study, our aim was to ... -
Clinical importance of discordance in hormone receptor and HER2/NEU status after neoadjuvant chemotherapy in breast cancer
Öven Ustaalioğlu, Bala Başak; Aker Vardar, Fügen; Bilici, Ahmet; Gürleyik, Günay; Erkol, Burçak; Kefeli, Umut (Elsevier, 2014)Aim: Neoadjuvant chemotherapy (NAC) is used longer for both locally advanced breast cancer and early stage to increase breast conservation. Discordance of the hormone receptor (HR) status was reported to be 8-33% of the ... -
Clinical importance of discordance of hormone receptors and Her2/neu status after neoadjuvant chemotherapy in breast cancer
Öven Ustaalioğlu, Bala Başak; Aker Vardar, Fügen; Bilici, Ahmet; Gürleyik, Günay; Erkol, Burçak; Kefeli, Umut; Aliustaoglu, Mehmet (Zerbinis Medical Publications, 2014)Purpose: The aim of this study was to compare the hormone receptors' (HR) and HER2/neu status between core needle biopsy (CNB) and residual tumor after surgery of breast cancer treated with neoadjuvant chemotherapy (NAC), ... -
The clinicopathologic characteristics and prognostic factors of gastroesophageal junction tumors according to Siewert classification
Öven Ustaalioğlu, Bala Başak; Tilki, Metin; Sümelioğlu, Ali; Bilici, Ahmet; Gönen, Can; Ustaalioğlu, Recep; Balvan, Özlem; Aliustaoğlu, Mehmet (AVES, 2017)Objective: The treatment of gastroesophageal junction tumors remains controversial due to confusion on whether they should be considered as primary esophageal or as gastric tumors. The incidence of these tumors with poor ... -
The comparison of local tumor control after microwave ablation, surgical resection and combined treatment for colorectal liver metastases
Güngören, Fatma Zeynep; Erol, Cengiz; Bilici, Ahmet; Dayangaç, Murat; Şeker, Mehmet; Ölmez, Ömer Fatih; Yaprak, Onur; Yıldız, Özcan; Öncel, Mustafa (ValpoScholar-Valparaiso University, 2022)Aim. We aimed to compare the local therapeutic efficiency of microwave ablation (MWA), surgical resection, and combined treatment, assess the outcomes, and identify predictive factors for local treatment response in ... -
Comparison of response and survival of first-line crizotinib therapy according to EML-4 ALK fusion variants in advanced non-small cell lung cancer patients: A Turkish Oncology Group study
Tatlı, Ali Murat; Yumuk, Perran Fulden; Öz, Büge; Bilici, Ahmet; Gürsoy, Pınar; Göker, Erdem; Sezer, Ahmet; Özet, Ahmet; Demirci, Umut; Bozkurtlar, Emine; Özbudak, İrem Hicran; Nart, Deniz; Canpolat, Tuğba; Akyürek, Nalan; Kılıçkap, Saadettin (Zerbinis Publications, 2021)Purpose: In the literature there are conflicting data about the treatment efficacy of anaplastic lymphoma kinase (ALK) translocation positive non-small cell lung cancer (NSCLC) patients according to ALK fusion variants. ... -
Comparison of skeletal muscle mass loss in patients with metastatic colorectal cancer treated with regorafenib or TAS-102
Hacıoğlu, Muhammet Bekir; Köstek, Osman; Kurt, Nazmi; Küçükarda, Ahmet; Gökyer, Ali; Ustabaşıoğlu, Fethi Emre; Karataş, Fatih; Tunçbilek, Nermin; Uzunoǧlu, Sernaz; Bilici, Ahmet; Çiçin, İrfan; Erdoğan, Bülent (Zerbinis Publications, 2019)Purpose: To assess whether regorafenib and TAS-102 treatments are associated with a change in Skeletal Muscle Area (SMA) as well as to compare Skeletal Muscle Mass (SMM) loss levels between regorafenib and TAS-102 treatments ... -
The conversion ofRASstatus in metastatic colorectal cancer patients after first-line biological agent treatment
Arıcı, Serdar; Hamdard, Jamshid; Sakin, Abdullah; Şengiz Erhan, Selma; Atçı, Muhammed Mustafa; Cekin, Ruhper; Saka, Burcu; Köse, Emin; Saydam, Tuba; Geredeli, Çağlayan; Cihan, Şener; Bilici, Ahmet (Wiley, 2021)Aim The aim was to investigate theRASdiscordance between initial and recurrent metastasectomy specimens in metastatic colorectal cancer (mCRC) patients treated with chemotherapy (CT) plus biological agents in a first-line ... -
Correlation of caveolin-1 expression with prognosis in patients with gastric cancer after gastrectomy
Şeker, Mesut; Aydın, Dinçer; Bilici, Ahmet; Yavuzer, Dilek; Özgün Geçer, Melin; Özçelik, Melike; Aydın, Özhan; Aliustaoğlu, Mehmet (Karger, 2017)Background: Upregulation of caveolin-1 (Cav-1) expression is correlated with histopathological grade and poor prognosis in several human cancers. However, in gastric cancer, its clinical utility as a useful prognostic ... -
Crizotinib efficacy and safety in patients with advanced NSCLC harboring MET alterations: A real-life data of Turkish Oncology Group
Gürbüz, Mustafa; Kılıçkap, Saadettin; Bilici, Ahmet; Karadurmuş, Nuri; Sezer, Ahmet; Şendur, Mehmet Ali Nahit; Paydaş, Semra; Artaç, Mehmet; Fulden Yumuk, Perran; Gürsoy, Pınar; Uysal, Mükremin; Şenol Coşkun, Hasan; Tatlı, Ali Murat; Selçukbiricik, Fatih; Dişel, Umut; Köksoy, Elif Berna; Güven, Deniz Can; Uğraklı, Muzaffer; Akkuş, Erman; Yücel, Şebnem; Erol, Cihan; Karakaya, Serdar; Şakalar, Teoman; Khanmammadov, Nijat; Paksoy, Nail; Demirkazık, Ahmet (NLM (Medline), 2022)Crizotinib is a multikinase inhibitor, effective in non-small cell lung cancer (NSCLC) harboring mesenchymal-epidermal transition (MET) alterations. Although small prospective studies showed efficacy and safety of crizotinib ...