Browsing by Author "Baştürk, Olca"
Now showing items 1-20 of 22
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Calculation of the Ki67 index in pancreatic neuroendocrine tumors: A comparative analysis of four counting methodologies
Reid, Michelle Dian; Bağcı, Pelin; Ohike, Nobuyuki; Saka, Burcu; Erbarut Seven, İpek; Dursun, Nevra; Balcı, Serdar; Gucer, Hasan; Jang, Kee-Taek; Tajiri, Takuma; Baştürk, Olca; Kong, So Yeon; Goodman, Michael; Akkaş, Gizem; Adsay, Volkan (Nature Publishing Group, 2015)Ki67 index is now an essential part of classification of pancreatic neuroendocrine tumors. However, its adaptation into daily practice has been fraught with challenges related to counting methodology. In this study, three ... -
Epithelial inclusions in the gallbladder: cytoisospora belli organisms or degenerative intracytoplasmic pas-positive hyaline globules
Pehlivanoğlu, Burçin; Erbarut Seven, İpek; Memiş, Bahar; Saka, Burcu; Bağcı, Pelin; Balcı, Serdar; Cheng, Jeanette; Baştürk, Olca; Reid, Michelle; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: Lai et al. reported 18 cases of Cystoisospora belli in the gallbladders (GBs), detected incidentally in 0.5% ofimmunocompetent patients (PMID: 27158759). However, a recent molecular study failed to confirm this ... -
Epithelial inclusions in the gallbladder: cytoisospora belli organisms or degenerative intracytoplasmic pas-positive hyaline globules
Pehlivanoğlu, Burçin; Erbarut Seven, İpek; Memiş, Bahar; Saka, Burcu; Bağcı, Pelin; Balcı, Serdar; Cheng, Jeanette; Baştürk, Olca; Reid, Michelle; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: Lai et al. reported 18 cases of Cystoisospora belli in the gallbladders (GBs), detected incidentally in 0.5% ofimmunocompetent patients (PMID: 27158759). However, a recent molecular study failed to confirm this ... -
Field risk ("field-effect"/"field-defect") in the gallbladder and biliary tree: An under-recognized phenomenon with major implications for management and carcinogenesis
Reid, Michelle; Losada, Hector; Muraki, Takashi; Pehlivanoğlu, Burçin; Memiş, Bahar; Koshiol, Jill; Bağcı, Pelin; Seven, İpek Erbarut; Balcı, Serdar; Saka, Burcu; Dursun, Nevra; Jang, Keetaek; Ohike, Nobuyuki; Tajiri, Takuma; Goodman, Michael; Carlos Roa, Juan; Araya, Juan; Bellolio, Enrique; Sarmiento, Juan; Xue, Yue; Baştürk, Olca; Adsay, Volkan (Nature Publishing Group, 2019)... -
Field risk ("field-effect"/"field-defect") in the gallbladder and biliary tree: An under-recognized phenomenon with major implications for management and carcinogenesis
Reid, Michelle; Losada, Hector; Muraki, Takashi; Pehlivanoğlu, Burçin; Memiş, Bahar; Koshiol, Jill; Bağcı, Pelin; Seven, İpek Erbarut; Balcı, Serdar; Saka, Burcu; Dursun, Nevra; Jang, Keetaek; Ohike, Nobuyuki; Tajiri, Takuma; Goodman, Michael; Carlos Roa, Juan; Araya, Juan; Bellolio, Enrique; Sarmiento, Juan; Xue, Yue; Baştürk, Olca; Adsay, Volkan (Nature Publishing Group, 2019)... -
Follicular cholecystitis: Reappraisal of incidence, definition, and clinicopathologic associations in an analysis of 2550 cholecystectomies
Saka, Burcu; Memiş, Bahar; Erbarut Seven, İpek; Pehlivanoğlu, Burçin; Balcı, Serdar; Bağcı, Pelin; Reid, Michelle; Dursun, Nevra; Tapia Escalano, Oscar; Carlos Roa, Juan; Carlos Araya, Juan; Kong, So Yeon; Baştürk, Olca; Koshiol, Jill; Adsay, N. Volkan (SAGE Publications Inc, 2020)Context.Follicular cholecystitis (FC) is a poorly characterized entity.Objective.To determine its frequency/clinicopathologic associations.Design.A total of 2550 cholecystectomy specimens were examined. Two hundred three ... -
Gallbladder polyps: Correlation of size and clinicopathologic characteristics based on updated definitions
Taşkın, Orhun C.; Baştürk, Olca; Reid, Michelle D.; Dursun, Nevra; Bağcı, Pelin; Saka, Burcu; Balcı, Serdar; Memiş, Bahar; Bellolio, Enrique; Araya, Juan Carlos; Roa, Juan Carlos; Tapia, Oscar; Losada, Hector; Sarmiento, Juan; Jang, Kee-Taek; Jang, Jin-Young; Pehlivanoğlu, Burçin; Erkan, Mert; Adsay, Volkan (Public Library of Science, 2020)Background Different perspectives exist regarding the clinicopathologic characteristics, biology and management of gallbladder polyps. Size is often used as the surrogate evidence of polyp behavior and size of >= 1cm is ... -
Histopathologic infiltration pattern predicts metastasis and progression better than pT-stage and grade in well-differentiated pancreatic neuroendocrine tumors: A proposal for an infiltration-based morphologic grading system
Taşkın, Orhun; Reid, Michelle; Bağcı Çulçi, Pelin; Balcı, Serdar; Armutlu, Ayşe; Demirtaş, Deniz; Pehlivanoğlu, Burçin; Saka, Burcu; Memiş, Bahar; Bozkurtlar, Emine; Leblebici, Can Berk; Corobea, Adelina Birceanu; Xue, Yue; Erkan, Mert; Kapran, Yersu; Sökmensüer, Cenk; Scarpa, Aldo; Luchini, Claudio; Baştürk, Olca; Adsay, Nazmi Volkan (Springer Nature, 2021)... -
Histopathologic infiltration pattern predicts metastasis and progression better than pT-stage and grade in well-differentiated pancreatic neuroendocrine tumors: A proposal for an infiltration-based morphologic grading system
Taşkın, Orhun; Reid, Michelle; Bağcı Çulçi, Pelin; Balcı, Serdar; Armutlu, Ayşe; Demirtaş, Deniz; Pehlivanoğlu, Burçin; Saka, Burcu; Memiş, Bahar; Bozkurtlar, Emine; Leblebici, Can Berk; Corobea, Adelina Birceanu; Xue, Yue; Erkan, Mert; Kapran, Yersu; Sökmensüer, Cenk; Scarpa, Aldo; Luchini, Claudio; Baştürk, Olca; Adsay, Nazmi Volkan (Springer Nature, 2021)... -
Is it justifiable to move the grade-1 ki67 index cut-off from 3% to 5% for pancreatic neuroendocrine tumors as has been proposed? The cases that fall to 3-5% category have clinicopathologic characteristics closer to those > 5%
Reid, Michelle; Balcı, Serdar; Bağcı, Pelin; Saka, Burcu; Pehlivanoğlu, Burçin; Erbarut Seven, İpek; Baştürk, Olca; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: Grading of linear parameters into meaningful (clinically relevant) clusters is a well-known challenge. Recently several groupshave proposed to change the Ki67 index cut-off for grade 1 (G1) category for PanNETs ... -
Is it justifiable to move the grade-1 ki67 index cut-off from 3% to 5% for pancreatic neuroendocrine tumors as has been proposed? The cases that fall to 3-5% category have clinicopathologic characteristics closer to those > 5%
Reid, Michelle; Balcı, Serdar; Bağcı, Pelin; Saka, Burcu; Pehlivanoğlu, Burçin; Erbarut Seven, İpek; Baştürk, Olca; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: Grading of linear parameters into meaningful (clinically relevant) clusters is a well-known challenge. Recently several groupshave proposed to change the Ki67 index cut-off for grade 1 (G1) category for PanNETs ... -
Non-neoplastic polyps of the gallbladder: A clinicopathologic analysis of 447 cases
Taşkın, Orhun; Bellolio, Enrique; Dursun, Nevra; Erbarut Seven, İpek; Roa, Juan C.; Araya, Juan C.; Villaseca, Miguel; Tapia, Oscar; Vance, Courtney; Saka, Burcu; Balcı, Serdar; Bağcı, Pelin; Losada, Hector; Sarmiento, Juan; Memis, Bahar; Pehlivanoğlu, Burçin; Baştürk, Olca; Reid, Michelle D.; Koshiol, Jill; Cheng, Jeanette; Kapran, Yersu; Adsay, Volkan (2020)There is no systematic histopathologic analysis of non-neoplastic polyps in the gallbladder. In this study, in addition to a computer search for cases designated as "polyp," a systematic review of 2533 consecutive routinely ... -
Pancreatic ductal adenocarcinoma is spread to the peripancreatic soft tissue in the majority of resected cases, rendering the AJCC T-stage protocol (7th Edition) inapplicable and Insignificant: A size-based staging system (pT1: ?2, pT2: >2–?4, pT3: >4 cm) is more valid and clinically relevant
Saka, Burcu; Balcı, Serdar; Baştürk, Olca; Bağcı, Pelin; Postlewait, Lauren Mc Lendon; Maithel, Shishir Kumar; Knight, Jessica; El Rayes, Bassel; Kooby, David; Sarmiento, Juan Martinez; Muraki, Takashi; Oliva, Irma; Bandyopadhyay, Sudeshna; Akkaş, Gizem; Goodman, Michael; Reid, Michelle Dian; Krasinskas, Alyssa; Everett, Rhonda; Adsay, Nazmi Volkan (Springer New York LLC, 2016)Background: Most studies have failed to identify any prognostic value of the current T-stage protocol for pancreatic ductal adenocarcinoma (PDAC) by the American Joint Committee on Cancer and the Union for International ... -
Poorly cohesive cell (diffuse-infiltrative/signet ring cell) carcinomas of the gallbladder: Clinicopathological analysis of 24 cases identified in 628 gallbladder carcinomas
Tuncel, Deniz; Carlos Roa, Juan; Carlos Araya, Juan; Bellolio, Enrique; Villaseca, Miguel; Tapia, Oscar; Jang, Kee-Taek; Quigley, Brian; Saka, Burcu; Baştürk, Olca; Sarmiento, Juan; Losada, Hector F.; Patel, Samip; Reid, Michelle D.; Memiş, Bahar; Adsay, Volkan (W B Saunders Co-Elsevier Inc, 2017)Signet ring cell carcinoma is an extremely rare type of gallbladder carcinoma: In the gastrointestinal system, carcinomas with single-cell or cord-like infiltration, previously called "diffuse-infiltrative" type or "signet ... -
A proposal for improved t-staging of pancreatic ductal adenocarcinoma by using microscopic examination as the basis for determining the size and t-stage
Baştürk, Olca; Reid, Michelle; Balcı, Serdar; Erbarut Seven, İpek; Saka, Burcu; Pehlivanoğlu, Burçin; Memis, Bahar; Bağcı, Pelin; Adsay, Nazmi Volkan (Nature Publishing Group, 2020)Background: Stage remains as the most helpful prognosticator in pancreatic ductal adenocarcinoma (PDAC). However, accurate grossmeasurement of PDAC tumor size, the main stage parameter, is a well-known challenge due to its ... -
A proposal for improved t-staging of pancreatic ductal adenocarcinoma by using microscopic examination as the basis for determining the size and t-stage
Baştürk, Olca; Reid, Michelle; Balcı, Serdar; Erbarut Seven, İpek; Saka, Burcu; Pehlivanoğlu, Burçin; Memis, Bahar; Bağcı, Pelin; Adsay, Nazmi Volkan (Nature Publishing Group, 2020)Background: Stage remains as the most helpful prognosticator in pancreatic ductal adenocarcinoma (PDAC). However, accurate grossmeasurement of PDAC tumor size, the main stage parameter, is a well-known challenge due to its ... -
Substaging nodal status in ampullary carcinomas has significant prognostic value: Proposed revised staging based on an analysis of 313 well-characterized cases
Balcı, Serdar; Baştürk, Olca; Saka, Burcu; Bağcı, Pelin; Postlewait, Lauren Mc Lendon; Tajiri, Takuma; Jang, Kee-taek; Ohike, Nobuyuki; Kim, Grace Eun Hye; Krasinskas, Alyssa; Choi, Hyejeong; Sarmiento, Juan Martinez; Kooby, David; El-Rayes, Bassel; Knight, Jessica; Goodman, Michael; Akkaş, Gizem; Reid, Michelle Dian; Maithel, Shishir Kumar; Adsay, Nazmi Volkan (Society of Surgical Oncology, 2015)Background: Current nodal staging (N-staging) of ampullary carcinoma in the TNM staging system distinguishes between node-negative (N0) and node-positive (N1) disease but does not consider the metastatic lymph node (LN) ... -
Substaging of lymph node status in resected pancreatic ductal adenocarcinoma has strong prognostic correlations: Proposal for a revised N classification for TNM staging
Baştürk, Olca; Saka, Burcu; Balcı, Serdar; Postlewait, Lauren Mc Lendon; Knight, Jessica; Goodman, Michael; Kooby, David; Sarmiento J.M.; El-Rayes, Bassel; Choi, Hyejeong; Bağcı, Pelin; Krasinskas, Alyssa; Quigley, Brian Christopher; Reid, Michelle Dian; Akkaş, Gizem; Maithel, Shishir Kumar; Adsay, Nazmi Volkan (Springer, 2015)Background: The current tumor-node-metastasis staging system for the pancreas does not incorporate the number of lymph nodes (LNs) with metastasis. Methods: Among 1649 pancreaticoduodenectomies, 227 stringently defined ... -
Whipple-ables: clinicopathologic comparison of 1032 cancers removed by pancreatoduodenectomy based on pathologic re-review using refined site-specific criteria
Balcı, Serdar; Reid, Michelle; Erbarut Seven, İpek; Saka, Burcu; Pehlivanoğlu, Burçin; Memiş, Bahar; Bağcı, Pelin; Baştürk, Olca; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: The literature is highly conflicted on the differential clinicopathologic characteristics of cancers arising from differentcompartments of the ampulla-pancreato-biliary tract and duodenum that are removed by ... -
Whipple-ables: clinicopathologic comparison of 1032 cancers removed by pancreatoduodenectomy based on pathologic re-review using refined site-specific criteria
Balcı, Serdar; Reid, Michelle; Erbarut Seven, İpek; Saka, Burcu; Pehlivanoğlu, Burçin; Memiş, Bahar; Bağcı, Pelin; Baştürk, Olca; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: The literature is highly conflicted on the differential clinicopathologic characteristics of cancers arising from differentcompartments of the ampulla-pancreato-biliary tract and duodenum that are removed by ...
