Browsing by Author "Aksan Kurnaz, Işıl"
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ETS-domain transcription factor Elk-1 mediates neuronal survival: SMN as a potential target
Demir, Özlem; Aysit, Neşe; Önder, Zeynep; Türkel, Nezaket; Öztürk, Gürkan; Sharrocks, Andrew D.; Aksan Kurnaz, Işıl (Elsevier, 2011)Elk-1 belongs to the ternary complex factors (TCFs) subfamily of the ETS domain proteins, and plays a critical role in the expression of immediate-early genes (IEGs) upon mitogen stimulation and activation of the ... -
Expression of Pea3 protein subfamily members in hippocampus and potential regulation following neuronal stimulation
Kandemir, Başak; Davis, Sabrina; Yiğit, Esra Nur; Öztürk, Gürkan; Yılmaz, Bayram; Laroche, Serge; Aksan Kurnaz, Işıl (Elsevier Ireland Ltd, 2020)Pea3 proteins belong to a subfamily of the E-twentysix (ETS) domain superfamily of transcription factors, which play various roles during development. Polyoma Enhancer-Activator 3 (Pea3) proteins Pea3, ERM and Er81 are ... -
Multiple sclerosis biomarker candidates revealed by cell-type-specific interactome analysis
Yurduseven, Kübra; Babal, Yigit Koray; Çelik, Eşref; Kerman, Bilal Ersen; Aksan Kurnaz, Işıl (Mary Ann Liebert, 2022)Multiple sclerosis (MS) is a demyelinating disorder that affects multiple regions of the central nervous system such as the brain, spinal cord, and optic nerves. Susceptibility to MS, as well as disease progression rates, ... -
Pea3 transcription factor promotes neurite outgrowth
Kandemir, Başak; Çağlayan, Berrak; Hausott, Barbara; Erdoğan, Burcu; Dağ, Uğur; Demir, Özlem; Savaşan Soğut, Melis; Klimaschewski, Lars; Aksan Kurnaz, Işıl (Frontiers Research Foundation, 2014)Pea3 subfamily of E-twenty six transcription factors consist of three major -exhibit branching morphogenesis, the function of Pea3 family in nervous system development and regeneration is only beginning to unfold. In this ...