Browsing by Author "Çalışkan, Tezcan"
Now showing items 1-14 of 14
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Are intervertebral disc tissue cells damaged when attempting to prevent thrombus formation using dabigatran, a new oral anticoagulant?
Kaplan, Necati; Karaaslan, Numan; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Akgün, Feride Sinem; Çalışkan, Tezcan; Şimşek, Abdullah Talha; Özbek, Hanefi (Turkish Neurosurgical Society, 2019)AIM: To investigate the effect of dabigatran, a new oral anticoagulant, on human primary cell cultures isolated from intact intervertebral disc tissue. MATERIAL and METHODS: Cell cultures were prepared from tissues obtained ... -
Are radio-contrast agents commonly used in discography toxic to the intact intervertebral disc tissue cells?
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Yaşar Şirin, Duygu; Kaplan, Necati; Çalışkan, Tezcan; Özdemir, Çiğdem; Akyuva, Yener; Ateş, Özkan (Wiley, 2019)In the literature, there have been no studies showing clear results on how radio-contrast pharmaceuticals would affect intact disc tissue cells. In this context, it was aimed to evaluate the effects of iopromide and gadoxetic ... -
Effect of naproxen on proliferation and differentiation of primary cell cultures isolated from human cartilage tissue
Karaarslan, Numan; Batmaz, Ahmet Güray; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Yaşar Şirin, Duygu; Kaplan, Necati; Öznam, Kadir; Ateş, Özkan (Spandidos Publications Ltd, 2018)Non-steroidal anti-inflammatory drugs (NSAIDs) that are applied through oral, injectable or topical routes have been widely used in painful and inflammatory musculoskeletal diseases. The current study aimed to determine ... -
The effectiveness of the amount of polymethylmethacrylate used in the treatment of lumbar osteoporotic compression fractures
Yüksel, Mehmet Onur; Çevik, Serdar; Erdoğan, Barış; Katar, Salim; Tunçkale, Tamer; Çalışkan, Tezcan; Ervan, Şevket (Yerküre Tanıtım ve Yayıncılık A.Ş., 2020)Objective: We aimed to investigate the effectiveness of the amount of polymethylmethacrylate used in pain control and maintenance of long-term vertebra corpus height in patients undergoing percutaneous vertebroplasty due ... -
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
Çalışkan, Tezcan; Şirin, Duygu Yaşar; Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Akyuva, Yener; Kaplan, Necati; Kaya, Yasin Emre; Şimşek, Abdullah Talha; Güzelant, Aliye Yıldırım; Ateş, Özkan (Spandidos Publications, 2019)The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ... -
The effects of NLR on the diagnosis and pharmacological management of brain abscesses
Çalışkan, Tezcan; Yılmaz, İbrahim; Hacıoğlu Kasım, Fatma Bahar; Ersöz, Emel; Doğan, Mustafa; Karaaslan, Numan (Alanya Alaaddin Keykubat University, 2021)Aim: The present study aims to examine the effectiveness of the neutrophil-tolymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Methods: In this retrospective study, radiological, neurological, ... -
The effects of rivaroxaban, an oral anticoagulant, on human IVD primary cultures
Çalışkan, Tezcan; Akalan, Hande; Yılmaz, İbrahim; Karaarslan, Numan; Yaşar Şirin, Duygu; Özbek, Hanefi (Termedia Publishing House Ltd, 2022)Introduction: The present study aimed to investigate the potential effects of rivaroxaban, an oral anticoagulant that inhibits the effects of factor Xa, on intact intervertebral disc tissue cells and the extracellular ... -
Evaluation of the effect of daptomycin, a glycopeptide agent, on intact intervertebral disc tissue
Kaplan, Necati; Yılmaz, İbrahim; Karaaslan, Numan; Yaşar Şirin, Duygu; Şimşek, Abdullah Talha; Çalışkan, Tezcan; Bircan, Rıfat; Özbek, Hanefi (Turkish Neurosurgical Society, 2019)AIM: To evaluate the effects of pre- and intra-operatively administered daptomycin (DAP) on the intact human primary intervertebral disc tissue cells. MATERIAL and METHODS: Primary cell cultures were established using ... -
Factors affecting on the prognosis in multiple intracranial aneurysms
Background: With improvements in diagnostic methods, the incidence of multiple intracranial aneurysms has increased up to 35%. Factors influential on outcome in multiple intracranial aneurysms are still debatable. We aimed ... -
The impact of various breast sizes of women on vertebral column and spinopelvic parameters
Tunçkale, Tamer; Özkan Gürdal, Sibel; Çalışkan, Tezcan; Topçu, Birol; Yüksel, Mehmet Onur (Turkish Neurological Society, 2021)AIM: To find out the anatomical changes in spine and pelvis, and the impact of various breast sizes of women on the quality of life. MATERIAL and METHODS: Sixty women with back pain volunteered to participate in this study. ... -
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
Akgün, Feride Sinem; Şirin, Duygu Yaşar; Yılmaz, İbrahim; Karaarslan, Numan; Özbek, Hanefi; Şimşek, Abdullah Talha; Kaya, Yasin Emre; Kaplan, Necati; Akyuva, Yener; Çalışkan, Tezcan; Ateş, Özkan (Spandidos Publications, 2019)The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ... -
Pain and neurogenic claudication control in lumbar stenosis, which is the most common cause of spinal surgery in the geriatric population
Yüksel, Mehmet Onur; Erdoğan, Barış; Üşen, Ahmet; Tunçkale, Tamer; Çalışkan, Tezcan (NLM (Medline), 2023)OBJECTIVES: The authors aim to present when to do physical therapy or surgery in geriatric patients with degenerative lumbar stenosis. METHODS: The authors retrospectively analyzed 250 patients who underwent physical therapy ... -
Systematic evaluation of desmopressin administered to patients with aneurysmal subarachnoid hemorrhage in the light of the literature
Karaarslan, Numan; Yılmaz, İbrahim; Akgün, Feride Sinem; Çalışkan, Tezcan; Özbek, Hanefi; Ateş, Özkan (Turkish Neurosurgical Society, 2020)AIM: To discuss the management of patients with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) developing after subarachnoid hemorrhage, in a comparative manner in the light of the literature.MATERIAL ... -
Systematic evaluation of promising clinical trials-gene silencing for the treatment of glioblastoma
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Topuk, Savaş; Yaşar Şirin, Duygu; Ateş, Özkan (Turkish Neurosurgical Society, 2019)AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...
