Ara
Toplam kayıt 3, listelenen: 1-3
Molecular modelling and activity analysis of mycobacterium tuberculosis DNA gyrase B ATPase active site
(University of Istanbul, 2017)
Computer-based algorithms and statistical techniques such as receiver operating characteristic (ROC) curves are increasingly used for the design of new ligands. X-ray crystallographic data and homology models allow examining ...
Molecular modelling and compound activity of the escherichia coli and staphylococcus aureus DNA gyrase B ATPase site
(University of Istanbul, 2017)
Development of new treatment ligands that can distinguish Escherichia coli (E. coli) from Staphylococcus aureus (S. aureus) is important because of bacterium multiple drug resistance. High-throughput virtual screening ...
Synthesis, antimicrobial activity and modeling studies of thiazoles bearing pyridyl and triazolyl scaffolds
(Walter de Gruyter GmbH, 2022)
In this study, novel 4-(5-((2/3/4-substituted benzyl)thio)-4-(4-substituted phenyl)-4H-1,2,4-triazol-3-yl)-2-(pyridin-3/4-yl)thiazoles were synthesized following a multi-step synthetic procedure. All the compounds were ...