dc.contributor.author | Buetti, Niccolò | |
dc.contributor.author | Tabah, Alexis | |
dc.contributor.author | Loiodice, Ambre | |
dc.contributor.author | Ruckly, Stéphane | |
dc.contributor.author | Aslan, Abdullah Tarık | |
dc.contributor.author | Montrucchio, Giorgia | |
dc.contributor.author | Cortegiani, Andrea | |
dc.contributor.author | Saltoğlu, Neşe | |
dc.contributor.author | Kayaaslan, Bircan | |
dc.contributor.author | Aksoy, Firdevs | |
dc.contributor.author | Murat, Akova | |
dc.contributor.author | Akdoğan, Özlem | |
dc.contributor.author | Saraçoğlu, Kemal Tolga | |
dc.contributor.author | Erdoğan, Cem | |
dc.contributor.author | Leone, Marc | |
dc.contributor.author | Ferrer, Ricard | |
dc.contributor.author | Paiva, José-Artur | |
dc.contributor.author | Hayashi, Yoshiro | |
dc.contributor.author | Ramanan, Mahesh | |
dc.contributor.author | Conway Morris, Andrew | |
dc.contributor.author | Barbier, François | |
dc.contributor.author | Timsit, Jean-François | |
dc.contributor.author | Lipman, Jeffrey | |
dc.contributor.author | Litton, Edward | |
dc.contributor.author | Palermo, Anna Maria | |
dc.contributor.author | Yap, Timothy | |
dc.contributor.author | Eroğlu, Ege | |
dc.contributor.author | Hosokawa, Koji | |
dc.contributor.author | Yoshida, Hideki | |
dc.contributor.author | Fujitani, Shigeki | |
dc.contributor.author | Zand, Farid | |
dc.contributor.author | Mahmoodpoor, Ata | |
dc.contributor.author | Tabatabaei, Seyed Mohammad Nasirodin | |
dc.contributor.author | Elrabi, Omar | |
dc.contributor.author | Almekhlafi, Ghaleb A. | |
dc.contributor.author | Vidal, Gabriela | |
dc.contributor.author | Aparicio, Marta | |
dc.contributor.author | Alonzo, Irene | |
dc.contributor.author | Namendys-Silva, Silvio A. | |
dc.contributor.author | Hermosillo, Mariana | |
dc.contributor.author | Castillo, Roberto Alejandro | |
dc.contributor.author | De Bus, Liesbet | |
dc.contributor.author | De Waele, Jan | |
dc.contributor.author | Hollevoet, Isabelle | |
dc.contributor.author | De Schryver, Nicolas | |
dc.contributor.author | Serck, Nicolas | |
dc.contributor.author | Kovacevic, Pedja | |
dc.contributor.author | Zlojutro, Biljana | |
dc.contributor.author | Ruppe, Etienne | |
dc.contributor.author | Montravers, Philippe | |
dc.contributor.author | Dulac, Thierry | |
dc.contributor.author | Castanera, Jérémy | |
dc.contributor.author | Massri, Alexandre | |
dc.contributor.author | Guesdon, Charlotte | |
dc.contributor.author | Garcon, Pierre | |
dc.contributor.author | Duprey, Matthieu | |
dc.contributor.author | Philippart, François | |
dc.contributor.author | Tran, Marc | |
dc.contributor.author | Bruel, Cédric | |
dc.contributor.author | Kalfon, Pierre | |
dc.date.accessioned | 2022-10-31T06:38:31Z | |
dc.date.available | 2022-10-31T06:38:31Z | |
dc.date.issued | 2022 | en_US |
dc.identifier.citation | Buetti, N., Tabah, A., Loiodice, A., Ruckly, S., Aslan, A. T., Montrucchio, G. ... Kalfon, P. (2022). Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: A descriptive analysis of the Eurobact II study. Critical Care, 26(1). https://doi.org/10.1186/s13054-022-04166-y | en_US |
dc.identifier.issn | 1364-8535 | |
dc.identifier.issn | 1466-609X | |
dc.identifier.uri | https://doi.org/10.1186/s13054-022-04166-y | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/9890 | |
dc.description.abstract | Background: The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 and non-COVID-19 critically ill patients. Methods: We used data from the Eurobact II study, a prospective observational multicontinental cohort study on HABSI treated in ICU. For the current analysis, we selected centers that included both COVID-19 and non-COVID-19 critically ill patients. We performed descriptive statistics between COVID-19 and non-COVID-19 in terms of patients’ characteristics, source of infection and microorganism distribution. We studied the association between COVID-19 status and mortality using multivariable fragility Cox models. Results: A total of 53 centers from 19 countries over the 5 continents were eligible. Overall, 829 patients (median age 65 years [IQR 55; 74]; male, n = 538 [64.9%]) were treated for a HABSI. Included patients comprised 252 (30.4%) COVID-19 and 577 (69.6%) non-COVID-19 patients. The time interval between hospital admission and HABSI was similar between both groups. Respiratory sources (40.1 vs. 26.0%, p < 0.0001) and primary HABSI (25.4% vs. 17.2%, p = 0.006) were more frequent in COVID-19 patients. COVID-19 patients had more often enterococcal (20.5% vs. 9%) and Acinetobacter spp. (18.8% vs. 13.6%) HABSIs. Bacteremic COVID-19 patients had an increased mortality hazard ratio (HR) versus non-COVID-19 patients (HR 1.91, 95% CI 1.49–2.45). Conclusions: We showed that the epidemiology of HABSI differed between COVID-19 and non-COVID-19 patients. Enterococcal HABSI predominated in COVID-19 patients. COVID-19 patients with HABSI had elevated risk of mortality. Trial registration ClinicalTrials.org number NCT03937245. Registered 3 May 2019. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | BioMed Central Ltd | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Bacteremia | en_US |
dc.subject | Bloodstream Infection | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Enterococcus | en_US |
dc.subject | ICU-Acquired | en_US |
dc.title | Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: A descriptive analysis of the Eurobact II study | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Critical Care | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-5715-8138 | en_US |
dc.identifier.volume | 26 | en_US |
dc.identifier.issue | 1 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1186/s13054-022-04166-y | en_US |
dc.institutionauthor | Erdoğan, Cem | |
dc.identifier.wosquality | Q1 | en_US |
dc.identifier.wos | 000869836500007 | en_US |
dc.identifier.scopus | 2-s2.0-85140066700 | en_US |
dc.identifier.pmid | 36258239 | en_US |
dc.identifier.scopusquality | Q1 | en_US |