dc.contributor.author | Tharakan, Tharu | |
dc.contributor.author | Bettocchi, Carlo | |
dc.contributor.author | Carvalho, Joana | |
dc.contributor.author | Corona, Giovanni | |
dc.contributor.author | Jones, Thomas Hugh | |
dc.contributor.author | Kadıoğlu, Ateş | |
dc.contributor.author | Martinez Salamanca, Juan Ignacio | |
dc.contributor.author | Şerefoğlu, Ege Can | |
dc.contributor.author | Verze, Paolo | |
dc.contributor.author | Salonia, Andrea | |
dc.contributor.author | Minhas, Suks | |
dc.date.accessioned | 2022-03-25T08:02:40Z | |
dc.date.available | 2022-03-25T08:02:40Z | |
dc.date.issued | 2022 | en_US |
dc.identifier.citation | Tharakan, T., Bettocchi, C., Carvalho, J., Corona, G., Jones, T. H., Kadıoğlu, A. ... Minhas, S. (2022). European association of urology guidelines panel on male sexual and reproductive health: A clinical consultation guide on the indications for performing sperm DNA fragmentation testing in men with infertility and testicular sperm extraction in nonazoospermic men. European Urology Focus, 8(1), 339-350. https://doi.org/10.1016/j.euf.2020.12.017 | en_US |
dc.identifier.issn | 2405-4569 | |
dc.identifier.uri | https://doi.org/10.1016/j.euf.2020.12.017 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/9165 | |
dc.description.abstract | Accumulating evidence has highlighted the contribution of oxidative stress and sperm DNA fragmentation (SDF) in the pathophysiology of male infertility. SDF has emerged as a novel biomarker of risk stratification for patients undergoing assisted reproductive technologies. Studies have also supported the use of testicular over ejaculated sperm at the time of intracytoplasmic sperm injection, as testicular sperm may have lower SDF than ejaculated samples. The European Association of Urology Working Panel on Male Sexual and Reproductive Health provides an evidence-based consultation guide on the indications for SDF testing in male infertility and also for testicular sperm extraction (TESE) in nonazoospermic men. We present the limitations and advantages of SDF testing and a framework to ensure that it is appropriately utilised in clinical practice. Furthermore, we critically appraise the current literature advocating the use of TESE in nonazoospermic men. Patient summary: This article reviews the evidence supporting the use of sperm DNA fragmentation testing in the assessment of male infertility and testicular sperm extrac-tion in nonazoospermic men. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Assisted Reproductive Technologies | en_US |
dc.subject | Male Infertility | en_US |
dc.subject | Sperm DNA Fragmentation | en_US |
dc.subject | Testicular Sperm Extraction | en_US |
dc.title | European association of urology guidelines panel on male sexual and reproductive health: A clinical consultation guide on the indications for performing sperm DNA fragmentation testing in men with infertility and testicular sperm extraction in nonazoospermic men | en_US |
dc.type | article | en_US |
dc.relation.ispartof | European Urology Focus | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-2530-7012 | en_US |
dc.identifier.volume | 8 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 339 | en_US |
dc.identifier.endpage | 350 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1016/j.euf.2020.12.017 | en_US |
dc.institutionauthor | Şerefoğlu, Ege Can | |
dc.identifier.wosquality | Q1 | en_US |
dc.identifier.wos | 000760997600045 | en_US |
dc.identifier.scopus | 2-s2.0-85099017314 | en_US |
dc.identifier.pmid | 33422457 | en_US |
dc.identifier.scopusquality | Q1 | en_US |