dc.contributor.author | Çakıcı, Çağrı | |
dc.contributor.author | Yiğitbaşı, Türkan | |
dc.contributor.author | Alagöz, Maide Hacer | |
dc.contributor.author | Yiğit, Pakize | |
dc.contributor.author | Emekli, Nesrin | |
dc.date.accessioned | 2021-11-05T07:55:18Z | |
dc.date.available | 2021-11-05T07:55:18Z | |
dc.date.issued | 2021 | en_US |
dc.identifier.citation | Çakıcı, Ç., Yiğitbaşı, T., Alagöz, M. H., Yiğit, P. ve Emekli, N. (2021). Relationship between interleukin 33 and tissue factor in non-diabetic and diabetic obese patients. Acta Pharmaceutica Sciencia, 59(4), 559-573. https://dx.doi.org/10.23893/1307-2080.APS.05934 | en_US |
dc.identifier.issn | 1307-2080 | |
dc.identifier.uri | https://dx.doi.org/10.23893/1307-2080.APS.05934 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/8569 | |
dc.description.abstract | The aim of the study is to investigate the relationship between tissue factor (TF) and Interleukin-33 (IL-33) and biochemical parameters in diabetic obese and non-diabetic obese patients. 21 healthy controls, 25 non-diabetic and 36 diabetic-obese patients were included in the study. While there was no difference between the groups in terms of IL-33 levels (p> 0.05), TF levels of diabetic obese group were statistically significantly higher than control group (p <0.05). HDL levels of the obese and diabetic obese groups were significantly lower than control group, and triglyceride, glucose, insulin, C-reactive protein (CRP), hemoglobin A1c (HbA1c), and HOMA-IR levels were significantly higher (p <0.05). A positive correlation was found between TF activity, and HbA1c and glucose levels (p <0.05). This suggests that TF may be predictive for diabetes which develop in the background of obesity, and that TF can be used as a prognostic value for diabetes. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Istanbul Medipol University | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Diabetes Mellitus | en_US |
dc.subject | Interleukin 33 | en_US |
dc.subject | Obesity | en_US |
dc.subject | Tissue Factor | en_US |
dc.title | Relationship between interleukin 33 and tissue factor in non-diabetic and diabetic obese patients | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Acta Pharmaceutica Sciencia | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik ve Tıp Bilişimi Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-8662-5284 | en_US |
dc.authorid | 0000-0002-0675-1839 | en_US |
dc.authorid | 0000-0002-5919-1986 | en_US |
dc.authorid | 0000-0002-0109-5086 | en_US |
dc.identifier.volume | 59 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 559 | en_US |
dc.identifier.endpage | 573 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.23893/1307-2080.APS.05934 | en_US |
dc.identifier.scopusquality | Q3 | en_US |