dc.contributor.author | Soysal, Ahmet | |
dc.contributor.author | Gönüllü, Erdem | |
dc.contributor.author | Arslan, Hüseyin | |
dc.contributor.author | Kibar, Büşra Sultan | |
dc.contributor.author | Pop, Serdar | |
dc.contributor.author | Yurttaş, Gözde Nur | |
dc.contributor.author | Demirbacak, Hacer | |
dc.contributor.author | Ünal, Füsun | |
dc.contributor.author | Öktem, Sedat | |
dc.contributor.author | Atıcı, Serkan | |
dc.contributor.author | Yücel Şen, Arife Derda | |
dc.contributor.author | Karabayır, Nalan | |
dc.contributor.author | Karaböcüoğlu, Metin | |
dc.date.accessioned | 2021-04-05T06:56:41Z | |
dc.date.available | 2021-04-05T06:56:41Z | |
dc.date.issued | 2021 | en_US |
dc.identifier.citation | Soysal, A., Gönüllü, E., Arslan, H., Kibar, B. S., Pop, S., Yurttaş, G. N. ... Karaböcüoğlu, M. (2021). Comparison of clinical and laboratory features and treatment options of 237 symptomatic and asymptomatic children infected with SARS-CoV-2 in the early phase of the COVID-19 pandemic in Turkey. Japanese Journal of Infectious Diseases, 74(4), 273-279. https://dx.doi.org/10.7883/yoken.JJID.2020.781 | en_US |
dc.identifier.issn | 1344-6304 | |
dc.identifier.issn | 1884-2836 | |
dc.identifier.uri | https://dx.doi.org/10.7883/yoken.JJID.2020.781 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/6684 | |
dc.description.abstract | Since the first report of COVID-19 in December 2019, little is known about therapeutic usage of hydroxychloroquine in pediatric patients with COVID-19. We retrospectively retrieved data for SARS-CoV-2 PCR positive pediatric patients from 20 hospitals in 8 different cities in Turkey. We obtained patients' epidemiological, clinical, laboratory features and drugs used for treatment of COVID-19. 237 nasopharyngeal swab SARS-CoV-2 PCR positive children were included into the study from March 26 to June 20, 2020. The mean age of asymptomatic children (118±62 months) was found to be higher than that of symptomatic children (89±69 months). Symptomatic children had a significantly lower mean lymphocyte count and higher mean CRP, D-dimer value, procalcitonin and LDH than asymptomatic children in univariate analysis. Out of 156 children, 78 (50%) children received Hydroxychloroquine-containing regimen, 15 of them were treated with hydroxychloroquine + azithromycin + oseltamivir, 44 were treated with hydroxychloroquine + azithromycin and 21 were only treated with hydroxychloroquine. Among the 156 patients who received medical treatment, 90 (58%) patients had pre and/or post-treatment ECG performed upon them. However, none of them either reported ECG abnormalities or a need for discontinuation of hydroxychloroquine because of adverse drug reaction. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | National Institute of Infectious Diseases | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Hydroxychloroquine | en_US |
dc.subject | SARS-CoV-2 | en_US |
dc.subject | Turkey | en_US |
dc.title | Comparison of clinical and laboratory features and treatment options of 237 symptomatic and asymptomatic children infected with SARS-CoV-2 in the early phase of the COVID-19 pandemic in Turkey | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Japanese Journal of Infectious Diseases | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-7950-2067 | en_US |
dc.authorid | 0000-0002-8003-1952 | en_US |
dc.identifier.volume | 74 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 273 | en_US |
dc.identifier.endpage | 279 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.7883/yoken.JJID.2020.781 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.scopusquality | Q3 | en_US |