Epileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study
View/ Open
Access
info:eu-repo/semantics/openAccessDate
2020Author
Uludüz, DeryaMidi, İpek
Duman, Taşkın
Yayla, Vildan
Karahan, Ali Yavuz
Afşar, Nazire
Özaydın Göksu, Eylem
Mengüllüoğlu, Necdet
Aytaç, Emrah
Sungur, Mehmet Ali
Yeşilot, Nilüfer
İnce, Birsen
Yalın, Osman Özgür
Oruç, Serdar
Şenol, Mehmet Güney
Yılmaz, Arda
Gökçe, Mustafa
Demirci, Seden
Yılmaz Küsbeci, Özge
Uzuner, Gülnur
Batur Çağlayan, Hale Zeynep
Açıkgöz, Mustafa
Kurucu, Hatice
Özdağ, Fatih
Baybaş, Sevim
Ekmekçi, Hakan
Çabala, Murat
Yaman, Mehmet
Yürekli, Vedat Ali
Tekeli, Hakan
Genç, Hamit
Utku, Uygar
Şahin, Şevki
Uçan Tokuç, Firdevs Ezgi
Uzuner, Nevzat
Bektaş, Hesna
Kablan, Yüksel
Karakurum Göksel, Başak
Milanlıoğlu, Aysel
Necioğlu Örken, Dilek
Aluçlu, Ufuk
Çolakoğlu, Sena
Tüfekçi, Ahmet
Bakar, Mustafa
Nazlıel, Bijen
Taşçılar, Nida Fatma
Göksan, Baki
Kozak, Hasan Hüseyin
Demir, Serkan
Mısırlı, Cemile Handan
Küçükoğlu, Hayriye
Çınar, Nilgün
Mayda Domaç, Füsun
Öztürk, Şerefnur
Güneş, Taşkın
Metadata
Show full item recordCitation
Uludüz, D., Midi, İ., Duman, T., Yayla, V., Karahan, A. Y., Afşar, N. ... Güneş, T. (2020). Epileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study. Seizure - European Journal of Epilepsy, 78, 113-117. https://dx.doi.org/10.1016/j.seizure.2020.02.017Abstract
Purpose: The aim of this study is to evaluate the presence and prognostic impact of early seizures in cerebral venous sinus thrombosis patients (CVST).Method: VENOST is a retrospective and prospective national multicenter observational study. CVST patients with or without epileptic seizures (ES) were analyzed and compared in terms of demographic and imaging data, causative factors, clinical variables, and prognosis in a total of 1126 patients.Results: The mean age of the patients in the ES group was 39.73 +/- 12.64 and 40.17 +/- 14.02 years in the non-ES group (p > 0.05). Epileptic seizures were more common (76.6 %) in females (p < 0.001). Early ES occurred in 269 of 1126 patients (23.9 %). Epileptic seizures mainly presented in the acute phase (71.4 %) of the disease (p < 0.001). Majority of these (60.5 %) were in the first 24 h of the CVST. The most common neurological signs were focal neurologic deficits (29.9 %) and altered consciousness (31.4 %) in the ES group. Superior sagittal sinus (SSS) and cortical veins (CV) involvement were the most common sites of thrombosis and the mostly related etiology were found puerperium in seizure group (30.3 % vs 13.9 %). Patients with seizures had worse outcome in the first month of the disease (p < 0.001) but these did not have any influence thereafter.Conclusions: In this largest CVST cohort (VENOST) reported female sex, presence of focal neurological deficits and altered consciousness, thrombosis of the SSS and CVs, hemorrhagic infarction were risk factors for ES occurrence in patients with CVST.
WoS Q Kategorisi
Q3Source
Seizure - European Journal of EpilepsyVolume
78Collections
- Makale Koleksiyonu [3650]
- PubMed İndeksli Yayınlar Koleksiyonu [4048]
- Scopus İndeksli Yayınlar Koleksiyonu [6284]
- WoS İndeksli Yayınlar Koleksiyonu [6432]