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Toplam kayıt 51, listelenen: 31-40
A different view on the pathophysiology of Parkinson’s disease: A descendent neurochemical hypothesis?
(Wolters Kluwer, 2019)
It has been already shown that Parkinson’s disease (PD) is characterized by a prominent degeneration in substantia nigra (SN)neurons. Growing evidence suggests that there is a latent period of PD associated with slight ...
Focused ultrasound and NXY-059 in experimental cerebral ischemia: A new therapeutic opportunity?
(Bentham Science Publishers, 2016)
troke is the third leading cause of morbidity and mortality worldwide. Many deleterious cellular pathways have been proposed to explain the molecular pathogenesis of this clinically devastating disease [1, 2]. The ...
DLPF targeted repetitive transcranial magnetic stimulation improves brain glucose metabolism along with the clinical and electrophysiological parameters in CBD patients
(Bentham Science Publishers, 2022)
Background: Corticobasal Degeneration (CBD) is a rare neurological disease caused by the pathological accumulation of tau protein. The primary pathological features of CBD include progressive neurodegenerative processes ...
FDG-PET scanning shows distributed changes in cortical activity associated with visual hallucinations in eye disease
(Bentham Science Publ Ltd, 2019)
Background and Objective: Charles Bonnet Syndrome (CBS) has been defined as complex visual hallucinations (CVH) due to visual loss. The underlying mechanism of CBS is not clear and the underlying pathophysiology of the ...
Pure posterior alien hand syndrome following a cerebrovascular lesion: Clinicoradiological correlates
(Korean Neurological Association, 2016)
Dear Editor, Alien hand syndrome (AHS) is a sensation of foreignness between the patient and one of his or her hands, where the affected hand is observed to perform autonomic purposive behaviors that are interpreted as ...
Accelerated forgetting and verbal memory consolidation process in idiopathic nondement Parkinson's disease
(Elsevier, 2019)
Objective: Episodic memory impairment and underlying pathophysiology in Parkinson's Disease (PD) is poorly investigated. Formerly, it was thought to be a secondary effect of impairment in fronto-striatal circuit. However, ...
Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?
(Wiley, 2017)
Sleep is an important factor that plays a key role in Alzheimer's disease pathogenesis. However, it is still unclear whether poor-quality sleep may overlap with sleep disturbances in the underlying dysfunctional mechanisms ...
Pramipexole responsive neck numbness: The therapeutic role of dopamine agonists in the spinal cord indicating to a common spinal pathophysiology with restless leg syndrome (RLS)?
(Bentham Science Publishers, 2016)
Background: There is still speculative data regarding the role of spinal dopaminergic neurotransmission in restless leg syndrome (RLS). Methods: We evaluated the therapeutic role of pramipexole in a patient with cervical ...
Therapeutic role of rifampicin in Alzheimer's disease
(Wiley, 2018)
Rifampicin exerts significant brain protective functions in multiple experimental models. Here we summarize the underlying mechanisms of the neuroprotective and pro-cognitive effects of rifampicin that are mediated by its ...
More evidence for the therapeutic role of pramipexole in upper limb restlessness due to cervical disc pathology?
(Bentham Science Publ Ltd, 2018)
Background: The causal link between upper limb restlessness and cervical disc prolapsus is still unclear, and the exact role of the spinal cord in the origination of limb restlessness is not yet completely understood. ...