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Toplam kayıt 418, listelenen: 11-20
Neonatal neurodegeneration in alzheimer's disease transgenic mouse model
(IOS Press, 2018)
Alzheimer's disease (AD) is a progressive disorder characterized by a variety of molecular pathologies causing cortical dementia with a prominent memory deficit. Formation of the pathology, which begins decades before the ...
Leaching of iron and chromium from an indigenous ferro chromium alloy via a rotary evaporator: Optimum conditions determination and kinetic analysis
(Elsevier, 2020)
In the leaching process of chromium-containing precursor hexavalent chromium may form, which provokes damages to environment and human health. As a solution, leaching the chromium containing precursor with sulphuric acid ...
Combined therapy with probiotic VSL#3 and Omega-3 fatty acids attenuates colonic injury and inflammation in chronic DNBS-induced colitis in mice
(Polish Academy of Sciences, 2021)
Inflammatory bowel disease (IBD) is a progressive chronic inflammatory disease affecting the gastrointestinal tract with a chronic relapsing and remitting disease course. While there are a number of therapeutic strategies ...
The effect of resveratrol on sphingosine-1 and oxidative/ nitrosative stress in an experimental heart ischemia reperfusion model
(University Press, 2022)
Objectives: Resveratrol (RSV) is a natural polyphenolic compound showing significant antioxidant effects. In this study, we aimed to investigate the effects of resveratrol on the sphingosine-1-phosphate (S1P) and oxidative ...
Protein kinaz C aktivatörü PMA’nın TRPV1 kanalları üzerindeki etkileri
(Hacettepe Üniversitesi, 2015)
TRP alt ailesinin bir üyesi olarak bilinen TRPV1 kanalları non-selektif katyon kanallarıdır. Bu kanalların en fazla bulunduğu dokular; arka kök gangliyon nöronları, vagal nöronlar ve trigeminal gangliyon nöronlarıdır. TRPV1 ...
An improved platform for cultured neuronal network electrophysiology: Multichannel optogenetics integrated with MEAs
(Springer, 2022)
Cultured neuronal networks (CNNs) are powerful tools for studying how neuronal representation and adaptation emerge in networks of controlled populations of neurons. To ensure the interaction of a CNN and an artificial ...
Effects of chromosomal translocations on sperm count in azoospermic and oligospermic cases
(Dokuz Eylül University Institute of Health Sciences, 2022)
Purpose: A number of mechanisms have been proposed for the effect of chromosomal translocations on spermatogenesis and sperm maturation. However, there are still numerous ambiguous issues regarding these two processes. The ...
What a single electroencephalographic (EEG) channel can tell us about alzheimer's disease patients with mild cognitive impairment
(NLM (Medline), 2023)
Abnormalities in cortical sources of resting-state eyes closed electroencephalographic (rsEEG) rhythms recorded by hospital settings (10-20 montage) with 19 scalp electrodes characterized Alzheimer's disease (AD) from ...
Instant determination of the artemisinin from various Artemisia annua L. extracts by LC-ESI-MS/MS and their in-silico modelling and in vitro antiviral activity studies against SARS-CoV-2
(Wiley, 2022)
Introduction Numerous efforts in natural product drug development are reported for the treatment of Coronavirus. Based on the literature, among these natural plants Artemisia annua L. shows some promise for the treatment ...
Phosphodiesterase 10A is a critical target for neuroprotection in a mouse model of ischemic stroke
(Springer, 2022)
Phosphodiesterase 10A (PDE10A) hydrolyzes adenosine 3 ',5 '-cyclic monophosphate (cAMP) and guanosine 3 ',5 '-cyclic monophosphate (cGMP). It is highly expressed in the striatum. Recent evidence implied that PDE10A may be ...