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Toplam kayıt 38, listelenen: 21-30
Artificial oocyte activation with calcium ionophore for frozen sperm cycles
(Taylor and Francis Ltd., 2018)
Fertilization problems are the major problems that may be faced in 30-55% of the patients during an intracytoplasmic sperm injection (ICSI) cycle. A successful oocyte activation depends on factors related to both sperm and ...
Effects of a thermosensitive in situ gel containing mometasone furoate on a rat allergic rhinitis model
(Sage Publications Inc, 2018)
Background: Mometasone furoate, one of the second generation intranasal corticosteroids, is currently used in suspension form due to its poor solubility. However, this is not favorable for nasal application because of the ...
Time-of-day dependent neuronal injury after ischemic stroke: Implication of circadian clock transcriptional factor bmal1 and survival kinase akt
(Humana Press Inc, 2018)
Occurrence of stroke cases displays a time-of-day variation in human. However, the mechanism linking circadian rhythm to the internal response mechanisms against pathophysiological events after ischemic stroke remained ...
Impaired melanocortin pathway function in prader-willi syndrome gene-magel2 deficient mice
(Oxford University Press, 2018)
Prader-Willi Syndrome (PWS) is a neurodevelopmental disorder causing social and learning deficits, impaired satiety and severe childhood obesity. Genetic underpinning of PWS involves deletion of a chromosomal region with ...
Effect of Ramadan fasting on glycemic control and other essential variables in diabetic patients
(Wolters Kluwer Medknow Publications, 2018)
Background: Fasting during the holy month of Ramadan is a religious obligation for all Muslims who represent 1.8 billion of the world population (24%). This study explores the effect of Ramadan fasting on the blood glucose, ...
Early stage alterations in CA1 extracellular region proteins indicate dysregulation of IL6 and iron homeostasis in the 5XFAD Alzheimer's disease mouse model
(Ios Press, 2018)
In recent years, an increasing number of research papers revealed that the compositional and volumetric alterations in the extracellular matrix are the consequences of aging and may be related to Alzheimer's disease (AD). ...
Effects of different drug treatments on the proliferation of human ovarian carcinoma cell line MDAH-2774
(Tubitak Scientific & Technical Research Council Turkey, 2018)
Background/aim: In this study, the effects of resveratrol as a natural polyphenol compound, gemcitabine as an antimetabolite that has nucleoside structure analogous to deoxycytidine, and para-aminophenol-derived paracetamol ...
Antiproliferative and apoptotic effects of onobrychis albiflora extract on HCT-116 cells
(Ondokuz Mayıs University, 2018)
In this study, the cytotoxic effects of the extracts of methanol: water (80:20) prepared from the above-ground parts of the varieties of Onobrychis albiflora Hub.-Mor., Onobrychis argyrea Boiss. subsp. argyrea, Onobrychis ...
Verteporfin mediated sequence dependent combination therapy against ovarian cancer cell line
(Elsevier Science Sa, 2018)
Ovarian Cancer is one of the deadliest gynecological cancer showing high resistance to chemotherapy. Non overlapping and synergistic combination therapies are the best option to overcome this multi-pathological silent ...
Effects of human sperm cryopreservation on apoptotic markers in normozoospermic and non-normozoospermic patients
(Cambridge University Press, 2018)
The negative effects of cryopreservation on sperm parameters are well documented but little information is known about molecular basis of the process. The aim of the present study was to investigate the possible effects ...