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Toplam kayıt 6, listelenen: 1-6
Glaucoma detection using image processing techniques: A literature review
(Elsevier, 2019)
The term glaucoma refers to a group of heterogeneous diseases that cause the degeneration of retinal ganglion cells (RGCs). The degeneration of RGCs leads to two main issues: (i) structural changes to the optic nerve head ...
A review of computational drug repositioning: Strategies, approaches, opportunities, challenges, and directions
(BMC, 2020)
Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an important role in optimizing the ...
Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy
(Bentham Science Publishers Ltd, 2018)
Cancer has become one of the main leading causes of morbidity and mortality worldwide. One of the critical drawbacks of current cancer therapeutics has been the lack of the target-selectivity, as these drugs should have ...
Utilization of biased G protein-coupled receptor signaling towards development of safer and personalized therapeutics
(MDPI, 2019)
G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have targeted this receptor family. Discovery of beta-arrestin ...
Prediction and targeting of interaction interfaces in g-rotein coupled receptor oligomers
(Bentham Science Publishers Ltd, 2018)
Background: Communication within a protein complex is mediated by physical interactions made among the protomers. Evidence for both the allosteric regulation present among the protomers of the protein oligomer and of the ...
A survey of machine learning-based methods for COVID-19 medical image analysis
(Springer Science and Business Media Deutschland GmbH, 2023)
The ongoing COVID-19 pandemic caused by the SARS-CoV-2 virus has already resulted in 6.6 million deaths with more than 637 million people infected after only 30 months since the first occurrences of the disease in December ...