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Toplam kayıt 74, listelenen: 7-26
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Can Carpobrotus edulis, heal incisional and excisional wounds on the skin?
(Comenius University, 2021)OBJECTIVES: This study aimed to investigate the wound healing activity of liposomal Carpobrotus edulis powder extract (CEPE) formulation on incisional and excisional wounds in rat. BACKGROUND: In the event of any damage, ... -
Catalytically competent non-transforming H-RASG12P mutant provides insight into molecular switch function and GAP-independent GTPase activity of RAS
(Nature Publishing Group, 2019)RAS mutants have been extensively studied as they are associated with development of cancer; however, H-RASG12P mutant has remained untouched since it does not lead to transformation in the cell. To the best of our knowledge, ... -
Characterization and biological evaluation of crataegus azarolus fruit polysaccharides
(Elsevier B.V., 2022)The polysaccharide obtained from Crataegus azarolus fruit, by water extraction followed by ethanol precipitation and fractionation using copper complex, shows physiological activities: prebiotic and antioxidant. The total ... -
Characterization of FcγRIa (CD64) as a ligand molecule for site-specific IgG1 capture: A side-by-side comparison with protein a
(American Chemical Society, 2022)Fc γreceptors (FcγRs) are one of the structures that can initiate effector function for monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal antibodies among all FcγRs. In this study, a ... -
Clinical evaluation of decompressive craniectomy in malignant middle cerebral artery infarction using 3d area and volume calculations
(Wolters Kluwer Medknow Publications, 2021)Objective: We aimed to measure the craniectomy area using three-dimensional (3D) anatomic area and volume calculations to demonstrate that it can be an effective criterion for evaluating survival and functional outcomes ... -
Comparison of protein expression profile of limb regeneration between neotenic and metamorphic axolotl
(Elsevier, 2020)The axolotl (Ambystoma mexicanum) salamander, a urodele amphibian, has an exceptional regenerative capacity to fully restore an amputated limb throughout the life-long lasting neoteny. By contrast, when axolotls are ... -
Complications of 2-level dynamic stabilization: A correlative clinical and radiological analysis at two-year follow-up on 103 patients
(Turkish Neurosurgical Society, 2018)AIM: To investigate the postoperative complications, such as screw loosening, screw breakage and adjacent segment disease (ASD), in patients who underwent surgery with 2-level dynamic stabilization systems. MATERIAL and ... -
Computational modeling of vascular growth in patient-specific pulmonary arterial patch reconstructions
(Elsevier Ltd, 2021)Recent progress in vascular growth mechanics has involved the use of computational algorithms to address clinical problems with the use of three-dimensional patient specific geometries. The objective of this study is to ... -
Curcumin- and Piperine-loaded emulsomes as combinational treatment approach enhance the anticancer activity of Curcumin on HCT116 colorectal cancer model
(Frontiers in Bioengineering and Biotechnology, 2020)Combination chemotherapy, administrating two chemotherapeutic agents concurrently, comes into prominence, as the heterogeneity or the level of the disease necessitates a collaborative action. Curcumin, isolated from turmeric, ... -
Cytotoxicity of standardized curcuminoids mixture against epithelial ovarian cancer cell line SKOV-3
(MDPI, 2020)Herbal medicine has been in use for centuries for a wide variety of ailments; however, the efficacy of its therapeutic agents in modern medicine is currently being studied. Curcuminoids are an example of natural agents, ... -
Delivery of curcumin within emulsome nanoparticles enhances the anti-cancer activity in androgen-dependent prostate cancer cell
(Springer, 2023)Background: Curcumin, a dietary polyphenol isolated from turmeric, is a potent phytochemical possessing intrinsic anticancer activities against various cancer types including prostate cancer. However, low water solubility ... -
Design of dense brush conformation bearing gold nanoparticles as theranostic agent for cancer
(Springer, 2019)Dense brush conformation–bearing theranostic agents are emerging as drug delivery systems due to their higher ability to escape from reticuloendothelial system uptake which prolongs their in vivo circulation time. With the ... -
Development of acoustically active nanocones using the host-guest interaction as a new histotripsy agent
(American Chemical Society, 2019)Histotripsy is a noninvasive and nonthermal ultrasound ablation technique, which mechanically ablates the tissues using very short, focused, high-pressured ultrasound pulses to generate dense cavitating bubble cloud. ... -
DU 145 insan prostat kanseri hücrelerinde Hsa-Mir-8072’nin potansiyel rolü
(Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, 2019)Amaç: Çalışmamızda, insan prostat kanser hücre hattı (DU145) ve prostat normal epitel hücre hatları (RWPE) arasında miRNA ifadesinin analizini yapmak ve kanser gelişiminde olası rolünü incelemeği amaçladık. Gereçler ve ... -
Effective PEGylation method to improve biocompatibility of graphene derivatives
(Elsevier, 2020)The research on the use of graphene (G) in the biological applications has increased exponentially with emerging concerns regarding its biosafety and potential cytotoxicity. The modification of the surface with biocompatible ... -
Effects of droplet composition on nanodroplet-mediated histotripsy
(Elsevier Science Inc, 2016)Nanodroplet-mediated histotripsy (NMH) is a targeted ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells. In two previous studies, polymer-encapsulated perfluoropentane ... -
Effects of ultrasound frequency on nanodroplet-mediated histotripsy
(Elsevier Science, 2015)Nanodroplet-mediated histotripsy (NMH) is a targeted ultrasound ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells for targeted tumor ablation. In a previous study, ... -
The efficacy of Staphylococcus aureus dry biomass in the detection of Cd(II) heavy metal ions
(Springer Nature, 2022)Environmental monitoring of heavy metal ions is vital due to their hazardous nature to living organisms. Among them, Cd(II) is a highly carcinogenic ion that interferes with the enzymatic reactions responsible for repairing ... -
Emulsomes meet s-layer proteins: An emerging targeted drug delivery system
(Bentham Science Publishers, 2015)Here, the use of emulsomes as a drug delivery system is reviewed and compared with other similar lipidic nanoformulations. In particular, we look at surface modification of emulsomes using S-layer proteins, which are ... -
Enhancing enzymatic properties of endoglucanase i enzyme from trichoderma reesei via swapping from cellobiohydrolase i enzyme
(MDPI, 2019)Utilizing plant-based materials as a biofuel source is an increasingly popular attempt to redesign the global energy cycle. This endeavour underlines the potential of cellulase enzymes for green energy production and ...