Synthesis and antiproliferative activity of 2-arylidene 6-(2-aryl-2-oxoethoxy) benzofuran-3-one derivatives
Göster/ Aç
Erişim
info:eu-repo/semantics/embargoedAccessTarih
2016Yazar
Demirayak, ŞerefYurttaş, Leyla
Karaburun, Ahmet Cağrı
Gündoğdu Karaburun, Nalan
Kayagil, İsmail
Üst veri
Tüm öğe kaydını gösterKünye
Demirayak, Ş., Yurttaş, L., Karaburun, A. Ç., Gündoğdu Karaburun, N. ve Kayagil, İ. (2016). Synthesis and antiproliferative activity of 2-arylidene 6-(2-aryl-2-oxoethoxy) benzofuran-3-one derivatives. Letters In Drug Design & Discovery, 13(6), 563-569. https://dx.doi.org/10.2174/1570180813999160429113316Özet
The synthesis of 2-arylidene 6-(2-aryl-2-oxoethoxy) benzofuran-3-one derivatives was reported and selected compounds were determined for their anticancer activity evaluation in National Cancer Institute NCI, USA according to the drug screening protocol of the institute against approximately 60 tumor cell lines derived from nine cancer diseases. Compound 3r, namely 2-(4-chlorobenzylidene)- 6-[2-(4-methoxyphenyl)-2-oxoethoxy] benzofuran-3-one exhibited the highest antitumor activity against non-small lung cancer cell lines.
WoS Q Kategorisi
Q4Scopus Q Kategorisi
Q2Kaynak
Letters In Drug Design & DiscoveryCilt
13Sayı
6Bağlantı
https://dx.doi.org/10.2174/1570180813999160429113316https://hdl.handle.net/20.500.12511/3382
Koleksiyonlar
- Makale Koleksiyonu [273]
- Scopus İndeksli Yayınlar Koleksiyonu [6271]
- WoS İndeksli Yayınlar Koleksiyonu [6416]