The determine of possible drug interaction of clarithromycin
Citation
Ceylan, C., Koçberber, E., Taner, N. ve Berk, B. (2016). The determine of possible drug interaction of clarithromycin. International Journal of Clinical Pharmacy içinde (1341-1341. ss.).Abstract
Phenytoin is an antiepileptic drug which is eliminated by CYP2C9, CYP2C19 (less important: CYP2C18, CYP3A4) enzyme. Therapeutic concentration range is very important due to the narrow therapeutic drug levels. Targeted therapeutic concentration range is 10–20 mg/L (40–80 lmol/L) in blood serum for adults and children older than 3 months. Phenytoin has highly variable pharmacokinetics due to its complex of binding to Albumin (%90). It is difficult to determine the correct dosage of this drug because of significant dose related toxicity. It is also important for inpatient in intensive care unit.
WoS Q Kategorisi
Q4Source
International Journal of Clinical PharmacyVolume
38Issue
5Collections
- Bildiri Koleksiyonu [34]
- WoS İndeksli Yayınlar Koleksiyonu [6433]