dc.contributor.author | Dayan, Akın | |
dc.contributor.author | Narin, Burcu | |
dc.contributor.author | Biteker, Murat | |
dc.contributor.author | Aksoy, Şükrü | |
dc.contributor.author | Fotbolcu, Hakan | |
dc.contributor.author | Duman, Dursun | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T19:51:50Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T19:51:50Z | |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | Dayan, A., Narin, B., Biteker, M., Aksoy, Ş., Fotbolcu, H. ve Duman, D. (2012). Coronary calcium score, albuminuria and inflammatory markers in type 2 diabetic patients: Associations and prognostic implications. Diabete Reseach and Clinical Practice, 98(1), 98-103. https://dx.doi.org/10.1016/j.diabres.2012.04.012 | en_US |
dc.identifier.issn | 0168-8227 | |
dc.identifier.issn | 1872-8227 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.diabres.2012.04.012 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/2293 | |
dc.description | WOS: 000311026100018 | en_US |
dc.description | PubMed ID: 22595190 | en_US |
dc.description.abstract | Aims: To investigate the relationship of coronary artery calcium (CAC) scores with common carotid artery intima media thickness (CCA-IMT), albuminuria and inflammatory factors in type 2 diabetes. Methods and results: 128 asymptomatic type 2 diabetic patients, with at least one cardiovascular risk factor in addition to diabetes, were included in the study. CAC scores, carotid arteries plaque formation and CCA-IMT were assessed. The patients were followed for a mean period of 36.6 +/- 3.3 months. Linear regression analysis identified the logarithmically transformed (Ln) albuminuria (beta = 0.32, P = 0.007), age (beta = 0.04, P = 0.001) and the uric acid (beta = 0.13, P = 0.04) as independent determinants of the CAC score. During follow-up period, cardiovascular events occurred in 18 out of 46 patients with CAC score >= 100 compared with 5 out of 82 patients with CAC score <100 (log rank, P < 0.0001). Multivariate Cox proportional hazards analysis identified LnCAC score (P < 0.0001), LnAlbuminuria (P = 0.01) and uric acid (P = 0.03) as independent predictors for cardiovascular events. Conclusions: There was a significant relationship between CAC score, albuminuria and inflammation in patients with type 2 diabetes. LnCAC score together with LnAlbuminuria and uric acid were identified as independent predictors of cardiovascular events in these patients. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Diabetes Mellitus | en_US |
dc.subject | Albuminuria | en_US |
dc.subject | Coronary Calcium score | en_US |
dc.subject | Inflammatory Marker | en_US |
dc.title | Coronary calcium score, albuminuria and inflammatory markers in type 2 diabetic patients: Associations and prognostic implications | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Diabete Reseach and Clinical Practice | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı | en_US |
dc.identifier.volume | 98 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 98 | en_US |
dc.identifier.endpage | 103 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1016/j.diabres.2012.04.012 | en_US |
dc.identifier.wosquality | Q1 | en_US |
dc.identifier.scopusquality | Q1 | en_US |