Assessment of 8-hydroxydeoxyguanosine levels in patients with preeclampsia: A prospective study
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2017Author
Akıncı, SezenÖzcan, Hüseyin Çağlayan
Balat, Özcan
Uğur, Mete Gürol
Öztürk, Ebru
Taysi, Seyithan
Sucu, Seyhun
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Akıncı, S., Özcan, H. Ç., Balat, Ö., Uğur, M. G., Öztürk, E., Taysi, S. ... Sucu, S. (2017). Assessment of 8-hydroxydeoxyguanosine levels in patients with preeclampsia: A prospective study. Clinical and Experimental Obstetrics & Gynecology, 44(2), 226-229. https://dx.doi.org/10.12891/ceog3474.2017Abstract
Purpose of investigation: To determine the levels of 8-hydroxydeoxyguanosine (8-OHdG) in preeclampsia (PE) using (enzyme linked immunosorbent assay (ELISA) method. Materials and Methods: Twenty-two pregnant women with severe PE, 18 pregnant women with mild PE, and 40 healthy pregnant women, all between 25 and 41 weeks of gestation, were enrolled in this prospective controlled study. 8-OHdG levels in maternal serum were measured using ELISA method. Results: The authors observed no statistically significant difference in 8-OHdG levels between the mild-severe PE and control groups (p = 0.208). Conclusion: The present results do not support the concept that 8-OHdG has a role in the etiopathogenesis of PE.
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Clinical and Experimental Obstetrics & GynecologyVolume
44Issue
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