| dc.contributor.author | Ulukan, Burge | |
| dc.contributor.author | Yiğit, Buket | |
| dc.contributor.author | Yılmaz, Onur | |
| dc.contributor.author | Cömert, Melis Cansu | |
| dc.contributor.author | Erkan, Mert | |
| dc.contributor.author | Adalı, Gupse | |
| dc.contributor.author | Dayangaç, Murat | |
| dc.contributor.author | Zeybel, Müjdat | |
| dc.date.accessioned | 10.07.201910:49:13 | |
| dc.date.accessioned | 2019-07-10T19:49:37Z | |
| dc.date.available | 10.07.201910:49:13 | |
| dc.date.available | 2019-07-10T19:49:37Z | |
| dc.date.issued | 2019 | en_US |
| dc.identifier.citation | Ulukan, B., Yiğit, B., Yılmaz, O., Cömert, M. C., Erkan, M., Adalı, G. ... Zeybel, M. (2019). DNA methylation pattern of TM6SF2 influences NAFLD progression in genotype-dependent manner. International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL) içinde (e549-e549. ss.). Vienna, Austria, April 10-14, 2019. https://dx.doi.org/10.1016/S0618-8278(19)31090-4 | en_US |
| dc.identifier.issn | 0168-8278 | |
| dc.identifier.issn | 1600-0641 | |
| dc.identifier.uri | https://dx.doi.org/10.1016/S0618-8278(19)31090-4 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/1680 | |
| dc.description | International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL) -- APR 10-14, 2019 -- Vienna, AUSTRIA | en_US |
| dc.description | WOS: 000463481702178 | en_US |
| dc.description.abstract | Background and aims: Non-alcoholic fatty liver disease (NAFLD) arises due to complex interaction of genetic and environmental factors. Evidence suggests that transmembrane 6 superfamily member 2 (TM6SF2) E167K variant is associated with NAFLD susceptibility and progression. The loss of function mutation in TM6SF2 plays a pivotal role in hepatic lipid accumulation, however, it remains unknown if there is an interplay between genetic and epigenetic mechanisms modifying disease pathogenesis. In this study, we aimed to investigate whether epigenetic marks of TM6SF2 could affect development of hepatic steatosis and fibrosis. | en_US |
| dc.description.sponsorship | European Assoc Study Liver | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Elsevier Science Bv | en_US |
| dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
| dc.subject | DNA | en_US |
| dc.subject | TM6SF2 | en_US |
| dc.subject | NAFLD | en_US |
| dc.subject | Ggenotype-Dependent Manner | en_US |
| dc.title | DNA methylation pattern of TM6SF2 influences NAFLD progression in genotype-dependent manner | en_US |
| dc.type | conferenceObject | en_US |
| dc.relation.ispartof | International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL) | en_US |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı | en_US |
| dc.authorid | 0000-0002-1240-7233 | en_US |
| dc.identifier.volume | 70 | en_US |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.startpage | e549 | en_US |
| dc.identifier.endpage | e549 | en_US |
| dc.relation.publicationcategory | Konferans Öğesi - Uluslararası - Kurum Öğretim Elemanı | en_US |
| dc.identifier.doi | 10.1016/S0618-8278(19)31090-4 | en_US |
| dc.identifier.wosquality | Q1 | en_US |
