Fabrication of naturel pumice/hydroxyapatite composite for biomedical engineering
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info:eu-repo/semantics/openAccessCC0 1.0 Universal (CC0 1.0) Public Domain Dedicationhttps://creativecommons.org/publicdomain/zero/1.0/Tarih
2016Yazar
Kömür, BaranLohse, Tim
Can, Hatice Merve
Khalilova, Gülnar
Geçimli, Zeynep Nur
Aydoğdu, Mehmet Onur
Kalkandelen, Cevriye
Stan, George E.
Şahin, Yeşim Müge
Şengil, Ahmet Zeki
Süleymanoğlu, Mediha
Kuruca Erdem, Serap
Oktar, Faik Nushet
Salman, Serdar
Ekren, Nazmi
Ficai, Anton
Gündüz, Oğuzhan
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Kömür, B., Lohse, T., Can, H. M., Khalilova, G., Geçimli, Z. N., Aydoğdu, M. O. ... Gündüz, O. (2016). Fabrication of naturel pumice/hydroxyapatite composite for biomedical engineering. BioMedical Engineering Online, 15(1), https://dx.doi.org/10.1186/s12938-016-0203-0Özet
Background: We evaluated the Bovine hydroxyapatite (BHA) structure. BHA powder was admixed with 5 and 10 wt% natural pumice (NP). Compression strength, Vickers micro hardness, Fourier transform infrared spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction studies were performed on the final NP-BHA composite products. The cells proliferation was investigated by MTT assay and SEM. Furthermore, the antimicrobial activity of NP-BHA samples was interrogated. Results: Variances in the sintering temperature (for 5 wt% NP composites) between 1000 and 1300 °C, reveal about 700 % increase in the microhardness (~100 and 775 HV, respectively). Composites prepared at 1300 °C demonstrate the greatest compression strength with comparable result for 5 wt% NP content (87 MPa), which are significantly better than those for 10 wt% and those that do not include any NP (below 60 MPa, respectively). Conclusion: The results suggested the optimal parameters for the preparation of NP-BHA composites with increased mechanical properties and biocompatibility. Changes in micro-hardness and compression strength can be tailored by the tuning the NP concentration and sintering temperature. NP-BHA composites have demonstrated a remarkable potential for biomedical engineering applications such as bone graft and implant.
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BioMedical Engineering OnlineCilt
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