dc.contributor.author | Karcı, Ebru | |
dc.contributor.author | Ürün, Yüksel | |
dc.contributor.author | Köksoy, Elif Berna | |
dc.contributor.author | Uçar, Gökhan | |
dc.contributor.author | Bilgin, Burak | |
dc.contributor.author | Yekedüz, Emre | |
dc.contributor.author | Arslan, Çağatay | |
dc.contributor.author | Alkan, Ali | |
dc.contributor.author | Dede, İsa | |
dc.contributor.author | Tuncay, Gülseren | |
dc.contributor.author | Hocazade, Cemil | |
dc.contributor.author | Yıldırım Özdemir, Nuriye | |
dc.contributor.author | Şendur, Mehmet Ali Nahit | |
dc.contributor.author | Utkan, Güngör | |
dc.contributor.author | Yalçın, Bülent | |
dc.contributor.author | Akbulut, Hakan | |
dc.date.accessioned | 2023-08-29T08:42:01Z | |
dc.date.available | 2023-08-29T08:42:01Z | |
dc.date.issued | 2022 | en_US |
dc.identifier.citation | Karcı, E., Ürün, Y., Köksoy, E. B., Uçar, G., Bilgin, B., Yekedüz, E. ... Akbulut, H. (2022). Predictive factor for lymph node metastasis in non-metastatic colorectal adenocarcinomas. Eurasian Journal of Medical Investigation, 6(3), 279-283. https://dx.doi.org/10.14744/ejmi.2022.37065 | en_US |
dc.identifier.issn | 2602-3164 | |
dc.identifier.uri | https://dx.doi.org/10.14744/ejmi.2022.37065 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/11374 | |
dc.description.abstract | Objectives: To evaluate the predictive factors of lymph node involvement in non-metastatic colorectal adenocarcinomas (nmCRC). Methods: A total of 453 patients diagnosed with nmCRC were analyzed regarding T stage, lymphovascular invasion status, tumor grade and proposed risk score (RS), determined by the combination of these three factors for lymph node metastasis. Results: The median age was 62 (25-90 years), M/F ratio was 1.4:1 and majority of the patients had tumors localized on the left colon (70.6%). The number of excised lymph nodes was ≥12 in 77% of the cases. The postoperative pathological assessments revealed that 57.2% of patie,nts had N0 disease, 29.1% had N1 disease, and 13.7% had N2 disease. The T stages (p=0.007), grade (p<0.001), lymphovascular invasion (p=0.002), RS (p<0.001), and number of excised lymph nodes (p=0.029) were significantly different between N0, N1, and N2 patients. Higher RS was associated with lymph node metastasis (p<0.001). Conclusion: The risk score may predict lymph node metastasis in patients with nmCRC and if validated may be helpful in the decision-making of adjuvant chemotherapy, especially in the elderly and patients with inadequate lymph node dissection. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Kare Publishing | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Attribution-NonCommercial 4.0 International | * |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Colorectal Adenocarcinomas | en_US |
dc.subject | Lymph Node Metastasis | en_US |
dc.subject | Predictive Factor | en_US |
dc.title | Predictive factor for lymph node metastasis in non-metastatic colorectal adenocarcinomas | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Eurasian Journal of Medical Investigation | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı | en_US |
dc.identifier.volume | 6 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 279 | en_US |
dc.identifier.endpage | 283 | en_US |
dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.14744/ejmi.2022.37065 | en_US |
dc.institutionauthor | Karcı, Ebru | |
dc.identifier.trdizinid | 1133889 | en_US |