Predictive value of C-reactive protein/albumin ratio for no-reflow in patients with Non-ST-elevation myocardial infarction
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info:eu-repo/semantics/openAccessAttribution 4.0 Internationalhttps://creativecommons.org/licenses/by/4.0/Date
2022Author
Tosu, Aydın RodiÇınar, Tufan
Kalyoncuoǧlu, Muhsin
Biter, Halil İbrahim
Çakal, Sinem
Çakal, Beytullah
Selçuk, Murat
Belen, Erdal
Can, Mehmet Mustafa
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Tosu, A. R., Çınar, T., Kalyoncuoǧlu, M., Biter, H. İ., Çakal, S., Çakal, B. ... Can, M. M. (2022). Predictive value of C-reactive protein/albumin ratio for no-reflow in patients with Non-ST-elevation myocardial infarction. Journal of Cardiovascular and Thoracic Research, 14(4), 214-219. https://dx.doi.org/10.34172/jcvtr.2022.30549Abstract
Introduction: The focus of this research was to explore the link between CRP (C-reactive protein)/albumin ratio (CAR), a novel inflammatory response marker, and no-reflow (NR) phenomena in non-ST elevation myocardial infarction (non-STEMI) patients during percutaneous coronary intervention (PCI). Methods: The current study recruited 209 non-STEMI participants who underwent PCI. The patients were divided into two groups based on their post-intervention Thrombolysis in Myocardial Infarction (TIMI) flow grade; those with and without NR. Results: In all, 30 non-STEMI patients (6.9%) had NR after PCI. CAR values were substantially greater in the NR group. The CAR was identified to be a determinant of the NR (OR: 1.250, 95% CI: 1.033-1.513, P = 0.02), although CRP and albumin were not independently related with NR in the multivariate analysis. In our investigation, low density lipoprotein-cholesterol levels and high thrombus burden were also predictors of the occurrence of NR. According to receiver operating characteristic curve evaluation, the optimal value of CAR was > 1.4 with 60% sensitivity and 47% specificity in detecting NR in non-STEMI patients following PCI. Conclusion: To the best of knowledge, this is the first investigation to demonstrate that the CAR, a new and useful inflammatory marker, can be utilized as a predictor of NR in patients with non-STEMI prior to PCI.
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Journal of Cardiovascular and Thoracic ResearchVolume
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