Yazar "Rokne, Jon George" için listeleme
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Exploring the prognostic significance of set-domain containing 2 (setd2) expression in advanced and castrate-resistant prostate cancer
Gamallat, Yaser; Felipe Lima, Joema; Seyedi, Sima; Li, Qiaowang; Rokne, Jon George; Alhajj, Reda; Ghosh, Sunita; Bismar, Tarek A. (2024)SET-domain containing 2 (SETD2) is a histone methyltransferase and an epigenetic modifier with oncogenic functionality. In the current study, we investigated the potential prognostic role of SETD2 in prostate cancer. A ... -
A review of computational drug repositioning: Strategies, approaches, opportunities, challenges, and directions
Jarada, Tamer N.; Rokne, Jon George; Alhajj, Reda (BMC, 2020)Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an important role in optimizing the ... -
Serrate RNA effector molecule (SRRT) is associated with prostate cancer progression and is a predictor of poor prognosis in lethal prostate cancer
Gamallat, Yaser; Choudhry, Muhammad; Li, Qiaowang; Rokne, Jon George; Alhajj, Reda; Abdelsalam, Ramy; Ghosh, Sunita; Arbet, Jaron; Boutros, Paul C.; Bismar, Tarek A. (MDPI, 2023)Arsenite-resistance protein 2, also known as serrate RNA effector molecule (ARS2/SRRT), is known to be involved in cellular proliferation and tumorigenicity. However, its role in prostate cancer (PCa) has not yet been ...