Yazar "Özçiçek, İlyas" için listeleme
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Design of IKVAV peptide/gold nanoparticle decorated, micro/nano-channeled PCL/PLGA film scaffolds for neuronal differentiation and neurite outgrowth
Aydeğer, Asel; Ayşit, Neşe; Baydaş, Gülsena; Çakıcı, Çağrı; Erim, Ümit Can; Arpa, Muhammet Davut; Özçiçek, İlyas (Elsevier Ltd, 2023)In the field of neural tissue engineering, intensive efforts are being made to develop tissue scaffolds that can support an effective functional recovery and neural development by guiding damaged axons and neurites. ... -
Development of BDNF/NGF/IKVAV peptide modified and gold nanoparticle conductive PCL/PLGA nerve guidance conduit for regeneration of the rat spinal cord injury
Özçiçek, İlyas; Ayşit, Neşe; Balçıkanlı, Zeynep; Ulaş Aytürk, Nilüfer; Aydeğer, Asel; Baydaş, Gülsena; Aydın, Mehmet Şerif; Altıntaş, Esra; Erim, Ümit Can (2024)Spinal cord injuries are very common worldwide, leading to permanent nerve function loss with devastating effects in the affected patients. The challenges and inadequate results in the current clinical treatments are leading ... -
The effects of gold nanoparticles with different surface coatings and sizes on biochemical parameters in mice
Özçiçek, İlyas; Çakıcı, Çağrı; Ayşit, Neşe; Erim, Ümit Can (Prusa Medical Publishing, 2023)Objectives: Gold nanoparticles are very popular metallic nanomaterials and they have a wide spectrum of biomedical applications. This study was aimed to the production of stable and monodisperse polyethyleneimine (PEI) and ... -
The effects of size, shape and surface functionality on in vivo biodistribution and toxicity: A multiparametric biochemical study of gold nanomaterials
Özçiçek, İlyas; Altuncu, N.; Çakıcı, Çağrı; Aydeğer, Asel (Wiley, 2021)Gold nanomaterials have a widespread use due to their superior physical and chemical properties. Gold nanoparticles and nanorods are very popular and stable metallic nanomaterials which can be synthesized easily in various ... -
The effects of surface functionality and size of gold nanoparticles on neuronal toxicity, apoptosis, ROS production and cellular/suborgan biodistribution
Özçiçek, İlyas; Ayşit, Neşe; Çakıcı, Çağrı; Aydeğer, Asel (Elsevier B.V., 2021)Gold nanoparticles are emerging as promising nanomaterials to create nanoscale therapeutic delivery systems. The aim of the study was to synthesis of highly monodisperse and stable gold nanoparticles functionalized with ... -
The effects of various surface coatings of gold nanorods on toxicity, neuronal localization, microstructural alterations, and in vitro/in vivo biodistribution
Özçiçek, İlyas; Ayşit, Neşe; Çakıcı, Çağrı; Ulaş Aytürk, Nilüfer; Aydeğer, Asel; Erim, Ümit Can (Wiley, 2022)With the development of gold nanorods (AuNRs) for a number of biomedical applications, understanding their various biological effects has become important. Surface functionalization of AuNRs is attracting increasing attention ... -
Histological changes in mice tissues induced by gold nanoparticles with different surface coatings and sizes
Özçiçek, İlyas; Ulaş Aytürk, Nilüfer (2022)Aim: Gold nanoparticles (AuNPs) have many biomedical applications due to their unique properties (e.g., chemical stability, optical properties, biocompatibility, easy synthesizability, and multiple functionalizations). ...