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Discovery of novel potent human chondrosarcoma (SW1353) inhibitors: 4-(2/3/4-pyridyl)thiazole 2-acetamide derivatives
Coşkun, Göknil Pelin; Şahin, Zafer; Erdoğan, Ömer; Çevik, Özge; Biltekin, Sevde Nur; Yurttaş, Leyla; Berk, Barkın; Ülgen, Mert; Demirayak, Şeref (Elsevier B.V., 2023)Chondrosarcoma is the most common cartilage sarcoma among adult patients. It is mainly observed after the degradation of chondrocytes in the case of cell stress. Unfortunately, the mortality among patients is high as a ... -
Predictive value of serum and follicular fluid chemerin concentrations during assisted reproductive cycles in women with polycystic ovary syndrome
Kabil Kucur, Suna; Kürek Eken, Meryem; Şanlı, İlhan; Kutlu, Tayfun; Bilgiç, Bülent Emre; Altuntaş, Şükriye Leyla; Çevik, Özge; Özkaya, Enis (Taylor and Francis Ltd., 2021)Aims To evaluate the effect of serum and follicular fluid (ff) Chemerin levels on Assisted Reproductive Technology (ART) outcomes in lean patients with PCOS. Materials and methods The study included 76 infertile reproductive ... -
Protective effects of momordica charantia (Bitter Melon) against metho-trexate-induced kidney damage
Macit, Çağlar; Özbeyli, Dilek; Çevik, Özge; Çetin, Melisa; Şener, Göksel; Özkan, Sevil (Bentham Science Publishers, 2023)Background: Methotrexate is a cytotoxic chemotherapeutic agent that has severe side ef-fects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ... -
Protective effects of momordica charantia (Bitter Melon) against methotrexate-induced kidney damage
Macit, Çağlar; Özbeyli, Dilek; Çevik, Özge; Çetin, Melisa; Şener, Göksel; Özkan, Sevil (Bentham Science Publishers Ltd., 2023)Background Methotrexate is a cytotoxic chemotherapeutic agent that has severe side effects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ...