• Dual action of exosomes derived from in vitro A beta toxicity model: The role of age for pathological response 

  Beker, Merve; Günay, Necmeddin; Sarıkamış, Bahar; Kalkan Çakmak, Rabia; Erçin, Nilüfer; Altıntaş, Mehmet Özgen; Altunay, Serdar; Beker, Mustafa Çağlar; Sarı Ak, Duygu; Kılıç, Ülkan (Elsevier Ireland Ltd, 2023)

  Exosomes released from different cell types of the central nervous system play an essential role in the patho-genesis of Alzheimer's disease (AD). In this study, we aimed to create an animal model by injecting exosomes ...

• Effect of painful electrical stimuli on readiness potential in the human brain 

  Dilek, Burcu; Osumi, Michihiro; Nobusako, Satoshi; Erdoğan, Sinem Burcu; Morioka, Shu (SAGE Publications Inc, 2022)

  The readiness potential (RP), which is a slow negative electrical brain potential that occurs before voluntary movement, can be interpreted as a measure of intrinsic brain activity originating from self-regulating mechanisms. ...

• Dual action of exosomes derived from in vitro Aβ toxicity model: The role of age for pathological response 

  Beker, Merve; Günay, Necmeddin; Sarıkamış, Bahar; Kalkan Çakmak, Rabia; Erçin, Nilüfer; Altıntaş, Mehmet Özgen; Altunay, Serdar; Beker, Mustafa Çağlar; Sarı Ak, Duygu; Kılıç, Ülkan (Elsevier Ireland Ltd, 2023)

  Exosomes released from different cell types of the central nervous system play an essential role in the pathogenesis of Alzheimer's disease (AD). In this study, we aimed to create an animal model by injecting exosomes that ...

• Investigation of hidden crisis of prescription drug abuse in Turkey: Pregabalin monitoring 

  Badur, İsa; Bilgin Badur, Naciye; Berk, Barkın (Istanbul Medipol University, 2022)

  This is a cross-sectional retrospective observational national study. Abuse/misuse of the pregabalin and related parameters analyzed. Pregabalin was mostly pre-scribed by general practitioners (26.2%). Pregabalin prescribing ...

• Reduced power and phase-locking values were accompanied by thalamus, putamen, and hippocampus atrophy in Parkinson's disease with mild cognitive impairment: An event-related oscillation study 

  Hünerli Gündüz, Duygu; Özbek İşbitiren, Yağmur; Uzunlar, Hakan; Çavuşoğlu, Berrin; Dönmez Çolakoğlu, Berril; Ada, Emel; Güntekin, Bahar; Yener, Görsev (Elsevier Inc., 2023)

  Parkinson's disease (PD) is a multifaceted neurodegenerative disorder accompanied by mild cognitive impairment (MCI) as a crucial nonmotor manifestation. Event-related oscillations (EROs) are suggested to reflect cognitive ...

• Functional evaluation of the tachycardia patient-derived iPSC cardiomyocytes carrying a novel pathogenic SCN5A variant 

  Şahoğlu Göktaş, Sevilay; Kazcı, Yusuf Enes; Tuncay, Erkan; Torun, Tuğçe; Akdeniz, Celal; Tuzcu, Volkan; Çağavi, Esra (Wiley, 2022)

  Tachycardia is characterized by high beating rates that can lead to life-threatening fibrillations. Mutations in several ion-channel genes were implicated with tachycardia; however, the complex genetic contributors and ...

• Can the imbalance between neurotrophic and apoptotic proteins be the "beware the ides of march" for unaffected relatives of schizophrenia patients? 

  Yeşilkaya, Ümit Haluk; Gıca, Şakir; Özkara Menekşeoğlu, Pelin; Güney Taşdemir, Büşra; Çıraklı, Zeynep; Karamustafalıoğlu, Nesrin (Springer, 2022)

  Schizophrenia (SZ) is a mental disorder with a strong genetic basis as well as epigenetic aspects. Siblings of patients with SZ can share certain endophenotypes with the patients, suggesting that siblings may be important ...

• Oscillatory delta and theta frequencies differentially support multiple items encoding to optimize memory performance during the digit span task 

  Aktürk, Tuba; de Graaf, Tom A.; Erdal, Furkan; Sack, Alexander T.; Güntekin, Bahar (Academic Press Inc., 2022)

  The human brain has limited storage capacity often challenging the encoding and recall of a long series of multiple items. Different encoding strategies are therefore employed to optimize performance in memory processes ...

• rs-fMRI analysis using spatio-temporal sparse convolutional neural networks 

  Yener, Fatma Muberr; Yıldız, Sultan; Hafeez, Muhammad Adeel; Kayasandık, Cihan Bilge; Doğan, Merve Yüsra (Institute of Electrical and Electronics Engineers Inc., 2022)

  Neuropsychiatric diseases such as Autism Spectrum Disorder (ASD) and Schizophrenia cause various behavioral and communication dysfunctions in human life. Resting state functional magnetic resonance imaging (rs-fMRI) is ...

• Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach 

  Kazcı, Yusuf Enes; Şahoğlu Göktaş, Sevilay; Aydın, Mehmet Şerif; Karadoğan, Behnaz; Nebol, Aylin; Turhan, Mehmet Uğurcan; Öztürk, Gürkan; Çağavi, Esra (Elsevier B.V., 2022)

  Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ...

• Treatment effects on event-related EEG potentials and oscillations in Alzheimer's disease 

  Yener, Görsev; Hünerli Gündüz, Duygu; Yıldırım, Ebru; Aktürk, Tuba; Başar Eroğlu, Canan; Bonanni, Laura; Del Percio, Claudio; Farina, Francesca; Ferri, Raffaele; Güntekin, Bahar; Hajós, Mihály; Ibáñez, Agustín; Jiang, Yang; Lizio, Roberta; Lopez, Susanna; Noce, Giuseppe; Parra, Mario A.; Randall, Fiona; Stocchi, Fabrizio; Babiloni, Claudio (Elsevier B.V., 2022)

  Alzheimer's disease dementia (ADD) is the most diffuse neurodegenerative disorder belonging to mild cognitive impairment (MCI) and dementia in old persons. This disease is provoked by an abnormal accumulation of amyloid-beta ...

• Duygudurum ve anksiyete bozukluklarında psikonöroimmünolojik süreçler ve psikoterapi ile ilişkisi 

  Yılmaz, Ceyhun; İkizer, Gözde (2022)

  Duygudurum ve anksiyete bozukluklarının yaygınlık oranlarının yüksekliği ve bu bozukluklarla ilişkili işlev bozuklukları nedeniyle, bu bozuklukların daha iyi anlaşılması, önlenmesi ve tedavi edilmesi oldukça önemlidir. ...

• Therapeutic role of repetitive transcranial magnetic stimulation in Alzheimer's and Parkinson's disease: Electroencephalography microstate correlates 

  Hanoğlu, Lütfü; Toplutaş, Eren; Sarıçaoğlu, Mevhibe; Velioğlu, Halil Aziz; Yıldız, Sultan; Yuluğ, Burak (Frontiers Media SA, 2022)

  Introduction: The microstate analysis is a method to convert the electrical potentials on the multi-channel electrode array to topographical electroencephalography (EEG) data. Repetitive transcranial magnetic stimulation ...

• Axillary microbiota is associated with cognitive impairment in parkinson's disease patients 

  Arıkan, Muzaffer; Yıldız, Zeynep; Kahraman Demir, Tuğçe; Helvacı Yılmaz, Nesrin; Şen, Aysu; Hanoğlu, Lütfü; Yıldırım, Süleyman (American Society for Microbiology, 2022)

  Cognitive impairment (CI) is among the most common non-motor symptoms of Parkinson's disease (PD), with a substantially negative impact on patient management and outcome. The development and progression of CI exhibits high ...

• Çalışma belleği görevi sırasındaki beyin hemodinamik yanıtlarının depresyon puanıyla ilişkisi 

  Vural, Özge (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2021)

  Depresyon, duygu durum bozukluklarının yanı sıra bellek, karar verme, psikomotor hız, dikkat gibi bilişsel işlevlerin de etkilendiği; psikososyal ve biyolojik birçok faktörden kaynaklanabilen karmaşık bir bozukluktur. ...

• Duygu düzenleme becerilerinin çalışma belleği ile ilişkisinin işlevsel yakın kızılötesi spektroskopi (fNIRS) ile değerlendirilmesi 

  Kodak, Rabia Nur (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2021)

  Duygu düzenleme, sosyal hayata adaptasyon için duygunun deneyimleme/ifade etme biçimini düzenlenmesi olarak açıklanmaktadır. Günlük hayatta sıklıkla "otomatik duygu düzenleme" kullanılmaktadır. Çalışma belleği (ÇB), günlük ...

• The correlation of non-motor symptoms and sleep on balance in Parkinson's disease patients with normal cognition and mild cognitive impairment 

  Sarıcaoğlu, Mevhibe; Helvacı Yılmaz, Nesrin; Özer, Fahriye Feriha; Hanoğlu, Lütfü (Springer London Ltd, 2021)

  Background Parkinson's disease (PD) is characterized by non-motor symptoms (NMS) as well as by motor symptoms. Together with the impairment of cognitive functions, NMS and sleep also affect motor symptoms negatively. The ...

• Intranasal levosimendan prevents cognitive dysfunction and apoptotic response induced by repeated isoflurane exposure in newborn rats 

  Demirgan, Serdar; Akyol, Onat; Temel, Zeynep; Şengelen, Aslıhan; Pekmez, Murat; Ulaş, Ozancan; Sevdi, Mehmet Salih; Erkalp, Kerem; Selcan, Ayşin (Springer, 2021)

  Anesthetic-induced toxicity in early life may lead to risk of cognitive decline at later ages. Notably, multiple exposures to isoflurane (ISO) cause acute apoptotic cell death in the developing brain and long-term cognitive ...

• Distinct brain oscillatory responses for the perception and identification of one's own body from other's body 

  Çelik, Samet; Doğan, Rümeysa Büşra; Parlatan, Cennet Sena; Güntekin, Bahar (Springer, 2021)

  The body recognition process includes complex visual processing, the sensation, perception, and distinction stages of the stimulus. This study examined this process by using the time-frequency analysis of EEG signals and ...

• Sinir hücreleri ile kalp kası hücreleri arasındaki etkileşimin moleküler ve elektrofizyolojik düzeyde araştırılması 

  Akgül Çağlar, Tüba (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2021)

  Kalbe dallanan otonom sinir sistemi ve duyu nöronları kalp kası hücreleri (kardiyomiyosit) ve kalbin çalışmasını düzenler. Kalpte oluşan ağrı, basınç ve gerilme gibi duyusal bilgilerin bağlantılı olduğu arka kök gangliyon ...

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