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dc.contributor.authorBabiloni, Claudio
dc.contributor.authorArakaki, Xianghong
dc.contributor.authorAzami, Hamed
dc.contributor.authorBennys, Karim
dc.contributor.authorBlinowska, Katarzyna
dc.contributor.authorBonanni, Laura
dc.contributor.authorBujan, Ana
dc.contributor.authorCarrillo, Maria C.
dc.contributor.authorCichocki, Andrzej
dc.contributor.authorde Frutos-Lucas, Jaisalmer
dc.contributor.authordel Percio, Claudio
dc.contributor.authorDubois, Bruno
dc.contributor.authorEdelmayer, Rebecca
dc.contributor.authorEgan, Gary
dc.contributor.authorEpelbaum, Stephane
dc.contributor.authorEscudero, Javier
dc.contributor.authorEvans, Alan
dc.contributor.authorFarina, Francesca
dc.contributor.authorFargo, Keith
dc.contributor.authorFernandez, Alberto
dc.contributor.authorFerri, Raffaele
dc.contributor.authorFrisoni, Giovanni
dc.contributor.authorHampel, Harald
dc.contributor.authorHarrington, Michael G.
dc.contributor.authorJelic, Vesna
dc.contributor.authorJeong, Jaeseung
dc.contributor.authorJiang, Yang
dc.contributor.authorKaminski, Maciej
dc.contributor.authorKavcic, Voyko
dc.contributor.authorKilborn, Kerry
dc.contributor.authorKumar, Sanjeev
dc.contributor.authorLam, Alice
dc.contributor.authorLim, Lew
dc.contributor.authorLizio, Roberta
dc.contributor.authorLopez, David
dc.contributor.authorLopez, Susanna
dc.contributor.authorLucey, Brendan
dc.contributor.authorMaestu, Fernando
dc.contributor.authorMcGeown, William J.
dc.contributor.authorMcKeith, Ian
dc.contributor.authorMoretti, Davide Vito
dc.contributor.authorNobili, Flavio
dc.contributor.authorNoce, Giuseppe
dc.contributor.authorOlichney, John
dc.contributor.authorOnofrj, Marco
dc.contributor.authorOsorio, Ricardo
dc.contributor.authorParra-Rodriguez, Mario
dc.contributor.authorRajji, Tarek
dc.contributor.authorRitter, Petra
dc.contributor.authorSoricelli, Andrea
dc.contributor.authorStocchi, Fabrizio
dc.contributor.authorTarnanas, Ioannis
dc.contributor.authorTaylor, John Paul
dc.contributor.authorTeipel, Stefan
dc.contributor.authorTucci, Federico
dc.contributor.authorValdes-Sosa, Mitchell
dc.contributor.authorValdes-Sosa, Pedro
dc.contributor.authorWeiergraeber, Marco
dc.contributor.authorYener, Görsev
dc.contributor.authorGüntekin, Bahar
dc.date.accessioned2021-10-21T12:18:40Z
dc.date.available2021-10-21T12:18:40Z
dc.date.issued2021en_US
dc.identifier.citationBabiloni, C., Arakaki, X., Azami, H., Bennys, K., Blinowska, K., Bonanni, L. ... Güntekin, B. (2021). Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panel. Alzheimer's and Dementia, 17(9), 1528-1553. https://dx.doi.org/10.1002/alz.12311en_US
dc.identifier.issn1552-5260
dc.identifier.issn1552-5279
dc.identifier.urihttps://dx.doi.org/10.1002/alz.12311
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8497
dc.description.abstractThe Electrophysiology Professional Interest Area (EPIA) and Global Brain Consortium endorsed recommendations on candidate electroencephalography (EEG) measures for Alzheimer's disease (AD) clinical trials. The Panel reviewed the field literature. As most consistent findings, AD patients with mild cognitive impairment and dementia showed abnormalities in peak frequency, power, and "interrelatedness" at posterior alpha (8-12 Hz) and widespread delta (< 4 Hz) and theta (4-8 Hz) rhythms in relation to disease progression and interventions. The following consensus statements were subscribed: (1) Standardization of instructions to patients, resting state EEG (rsEEG) recording methods, and selection of artifact-free rsEEG periods are needed; (2) power density and "interrelatedness" rsEEG measures (e.g., directed transfer function, phase lag index, linear lagged connectivity, etc.) at delta, theta, and alpha frequency bands may be use for stratification of AD patients and monitoring of disease progression and intervention; and (3) international multisectoral initiatives are mandatory for regulatory purposes.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectAlzheimer's Diseaseen_US
dc.subjectBiomarkersen_US
dc.subjectClinical Trialsen_US
dc.subjectDementiaen_US
dc.subjectElectroencephalography (EEG)en_US
dc.subjectEyes-Closed Resting State Conditionen_US
dc.subjectThe Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART)en_US
dc.titleMeasures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panelen_US
dc.typereviewen_US
dc.relation.ispartofAlzheimer's and Dementiaen_US
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)en_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyofizik Ana Bilim Dalıen_US
dc.authorid0000-0002-0860-0524en_US
dc.identifier.volume17en_US
dc.identifier.issue9en_US
dc.identifier.startpage1528en_US
dc.identifier.endpage1553en_US
dc.relation.publicationcategoryDiğeren_US
dc.identifier.doi10.1002/alz.12311en_US
dc.identifier.wosqualityQ1en_US
dc.identifier.scopusqualityQ1en_US


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