dc.contributor.author | Karabay, Oğuz | |
dc.contributor.author | Batırel, Ayşe | |
dc.contributor.author | Balkan, İlker İnanç | |
dc.contributor.author | Ağalar, Canan | |
dc.contributor.author | Akalın, Şerife | |
dc.contributor.author | Alıcı, Özlem | |
dc.contributor.author | Alp, Emine | |
dc.contributor.author | Aybala Alta, Fatma | |
dc.contributor.author | Altın, Nilgün | |
dc.contributor.author | Arslan, Ferhat | |
dc.contributor.author | Aslan, Turan | |
dc.contributor.author | Bekiroğlu, Nural | |
dc.contributor.author | Cesur, Salim | |
dc.contributor.author | Doğan Çelik, Aygül | |
dc.contributor.author | Doğan, Mustafa | |
dc.contributor.author | Durdu, Bülent | |
dc.contributor.author | Duygu, Fazilet | |
dc.contributor.author | Engin, Aynur | |
dc.contributor.author | Öztürk Engin, Derya | |
dc.contributor.author | Gönen, İbak | |
dc.contributor.author | Güçlü, Ertuğrul | |
dc.contributor.author | Güven, Tümer | |
dc.contributor.author | Ataman Hatipoğlu, Çiğdem | |
dc.contributor.author | Hoşoğlu, Salih | |
dc.contributor.author | Karahocagil, Mustafa | |
dc.contributor.author | Ulu Kılıç, Ayşegül | |
dc.contributor.author | Örmen, Bahar | |
dc.contributor.author | Özdemir, Davut | |
dc.contributor.author | Özer, Serdal | |
dc.contributor.author | Öztoprak, Nefise | |
dc.contributor.author | Sezak, Nurbanu | |
dc.contributor.author | Turhan, Vedat | |
dc.contributor.author | Türker, Nesrin | |
dc.contributor.author | Yılmaz, Hava | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T19:35:34Z | |
dc.date.available | 10.07.201910:49:14 | |
dc.date.available | 2019-07-10T19:35:34Z | |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | Karabay, O., Batırel, A., Balkan, İ. İ., Ağalar, C., Akalın, Ş., Alıcı, Ö. ... Yılmaz, H. (2014). Efficacy of colistin and non-colistin monotherapies in multi-drug resistant acinetobacter baumannii bacteremia/sepsis. Acta Medica Mediterranea, 30(5), 1137-1143. | en_US |
dc.identifier.issn | 0393-6384 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/848 | |
dc.description.abstract | Objective: This retrospective study aimed to investigate the efficacies of colistin and non-colistin monotherapies in multi-drug resistant Acinetobacter baumannii bacteremia (MDR-AB). Materials and methods: Cases with MDR-AB from 27 tertiary-referral hospitals between January 2009 and December 2012 were included. Patients' data that were on either colistin monotherapy (CM) or non-colistin monotherapy (NCM) were compared. Mortality on Day 14 was the primary endpoint, whereas microbiological eradication and clinical outcome were the secondary ones. Results: Eighty-four cases were included in the study with 36 being in the CM group and 48 in the NCM group. Thirty-eight (45.2%) cases were male and the mean age was 60.2 years. The mean durations of pre-MDR-AB hospital stay and intensive care unit stay were 25.8 days and 20.9 days, respectively. All of the cases had fever (>38°C). The mean Pitt bacteremia score (PBS) of the patients was calculated as 6.8, APACHE 2 score as 18.9 and the Charlson co-morbidity index (CCI) as 3.7 (CM: 3.6 vs. NCM: 3.9). Twenty (55.6%) cases in the CM group and 26 cases in the NCM group (54.2%) (p=0.81) died; 9 cases in the CM group (25%) and 16 cases in the NCM group (33.3%) had treatment failure (P=0.55). Bacteriological eradication was achieved in 20 (55.6%) cases in the CM group and in 36 cases (75%) in the NCM group (P=0.061). Conclusions: No significant difference could be identified between the colistin monotherapy and non-colistin monotherapy options in MDR-AB cases with respect to the results of efficacy and 14-day mortality. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Acta Medica Mediterranea | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Acinetobacter Baumannii | en_US |
dc.subject | Bacteremia | en_US |
dc.subject | Colistin | en_US |
dc.subject | Monotherapy | en_US |
dc.subject | Multi-Drug Resistant | en_US |
dc.subject | Sepsis | en_US |
dc.title | Efficacy of colistin and non-colistin monotherapies in multi-drug resistant acinetobacter baumannii bacteremia/sepsis | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Acta Medica Mediterranea | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0001-8554-7651 | en_US |
dc.identifier.volume | 30 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 1137 | en_US |
dc.identifier.endpage | 1143 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.scopusquality | Q4 | en_US |