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dc.contributor.authorPolat, Salih
dc.contributor.authorDanacıoğlu, Yavuz Onur
dc.contributor.authorSoytaş, Mustafa
dc.contributor.authorYarımoğlu, Serkan
dc.contributor.authorKoraş, Ömer
dc.contributor.authorFakir, Ali Emre
dc.contributor.authorŞeker, Kamil Gökhan
dc.contributor.authorDeğirmenci, Tansu
dc.date.accessioned2021-10-12T09:22:07Z
dc.date.available2021-10-12T09:22:07Z
dc.date.issued2021en_US
dc.identifier.citationPolat, S., Danacıoğlu, Y. O., Soytaş, M., Yarımoğlu, S., Koraş, Ö., Fakir, A. E. ... Değirmenci, T. (2021). External validation of the T.O.HO. score and derivation of the modified T.O.HO. score for predicting stone-free status after flexible ureteroscopy in ureteral and renal stones. International Journal of Clinical Practice, 75(10). https://dx.doi.org/10.1111/ijcp.14653en_US
dc.identifier.issn1368-5031
dc.identifier.urihttps://dx.doi.org/10.1111/ijcp.14653
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8432
dc.description.abstractObjective: The T.O.HO. scoring system was developed to predict stone-free status after flexible ureterenoscopy (fURS) lithotripsy applied for ureter and renal stones. This study aimed to perform the external validation of the T.O.HO. score in the Turkish population and propose a modification for this system. Material methods: Patients who underwent fURS for kidney and ureteral stones between January 2017 and January 2020 were retrospectively analysed. The patient and stone characteristics and perioperative findings were noted. The T.O.HO. score was externally validated and compared with the STONE score. Stone-free parameters were evaluated with the multivariate analysis. Based on the results of this analysis, the T.O.HO. score was modified and internally validated. Results: A total of 621 patients were included in the study. The stone-free rate was determined as 79.8% (496/621) after fURS. The regression analysis showed that stone area had better predictive power than stone diameter (P =.025). Lower pole (reference), middle pole [odds ratio (OR) = 0.492 P =.016] and middle ureteral (OR = 0.227, P =.024) localisations, stone density (OR = 1.001, P <.001), and stone volume (OR = 1.008, P <.001) were determined as independent predictive markers for stone-free status. Based on the effect size of the stone surface area in the nomogram, stone volume was divided into five categories, at 1-point intervals. The AUC values of the T.O.HO., STONE, and modified T.O.HO. score in predicting stone-free status were calculated as 0.758, 0.634, and 0.821, respectively. The modified T.O.HO. created by adding stone volume was statistically significantly superior to the original version (ROC curve comparison, P <.001). Conclusion: The T.O.HO. score effectively predicted stone-free status after fURS. However, modified T.O.HO. SS showed the best predictive performance compared with original T.O.HO. SS.en_US
dc.language.isoengen_US
dc.publisherJohn Wiley and Sons Incen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFlexible Ureteroscopyen_US
dc.subjectRenal Stonesen_US
dc.subjectT.O.HO. Scoreen_US
dc.titleExternal validation of the T.O.HO. score and derivation of the modified T.O.HO. score for predicting stone-free status after flexible ureteroscopy in ureteral and renal stonesen_US
dc.typearticleen_US
dc.relation.journalInternational Journal of Clinical Practiceen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalıen_US
dc.authorid0000-0002-3474-3510en_US
dc.identifier.volume75en_US
dc.identifier.issue10en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1111/ijcp.14653en_US


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