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dc.contributor.authorÇakar, Engin
dc.contributor.authorAkyüz, Gülseren
dc.contributor.authorDurmuş, Oǧuz
dc.contributor.authorBayman, Levent
dc.contributor.authorYağcı, İlker
dc.contributor.authorKaradağ Saygı, Evrim
dc.contributor.authorGündüz, Osman Hakan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:35:31Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:35:31Z
dc.date.issued2016en_US
dc.identifier.citationÇakar, E., Akyüz, G., Durmuş, O., Bayman, L., Yağcı, İ., Karadağ Saygı, E. ... Gündüz, O. H. (2016). The relationships of motor-evoked potentials to hand dexterity, motor function, and spasticity in chronic stroke patients: a transcranial magnetic stimulation study. Acta Neurologica Belgica, 116(4), 481-487. https://dx.doi.org/10.1007/s13760-016-0633-2en_US
dc.identifier.issn0300-9009
dc.identifier.urihttps://hdl.handle.net/20.500.12511/826
dc.identifier.urihttps://dx.doi.org/10.1007/s13760-016-0633-2
dc.description.abstractThe standardization of patient evaluation and monitoring methods has a special importance in evaluating the effectiveness of therapeutic methods using drugs or rehabilitative techniques in stroke rehabilitation. The aim of this study was to investigate the relationships between clinical instruments and transcranial magnetic stimulation (TMS)-evoked neurophysiological parameters in stroke patients. This study included 22 chronic post-stroke patients who were clinically assessed using the Motricity Index (MI), finger-tapping test (FTT), Motor Activity Log (MAL) 28, Brunnstrom motor staging and Ashworth Scale (ASH). Motor-evoked potential (MEP) latency and amplitude, resting motor threshold (rMT) and central motor conduction time (CMCT) were measured with TMS. Shorter MEP-latency, shorter CMCT, higher motor-evoked potential amplitude, and diminished rMT exhibited significant correlations with clinical measures evaluating motor stage, dexterity, and daily life functionality. rMT exhibited a negative correlation with hand and lower extremity Brunnstrom stages (r = -0.64, r = -0.51, respectively), MI score (r = -0.48), FTT score (r = -0.69), and also with amount of use scale and quality of movement scale of MAL 28 scores (r = -0.61, r = -0.62, respectively). Higher MEP amplitude and diminished rMT showed positive correlations with reduced ASH score (r = -0.65, r = 0.44, respectively). The TMS-evoked neurophysiologic parameters including MEP latency, amplitude, rMT and CMCT generally have positive correlation with clinical measures which evaluate motor stage, dexterity and daily life functionality. Additionally, spasticity has also remarkable relationships with MEP amplitude and rMT. These results suggest that TMS-evoked neurophysiological parameters were useful measures for monitoring post-stroke patients.en_US
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDexterityen_US
dc.subjectMotor-Evoked Potentialen_US
dc.subjectNeurorehabilitationen_US
dc.subjectSpasticityen_US
dc.subjectTranscranial Magnetic Stimulationen_US
dc.titleThe relationships of motor-evoked potentials to hand dexterity, motor function, and spasticity in chronic stroke patients: A transcranial magnetic stimulation studyen_US
dc.typearticleen_US
dc.relation.journalActa Neurologica Belgicaen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalıen_US
dc.authorid0000-0003-4095-2076en_US
dc.identifier.volume116en_US
dc.identifier.issue4en_US
dc.identifier.startpage481en_US
dc.identifier.endpage487en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1007/s13760-016-0633-2en_US


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