dc.contributor.author | Fotbolcu, Hakan | |
dc.contributor.author | Duman, Dursun | |
dc.contributor.author | Alışır Ecder, Sebahat | |
dc.contributor.author | Oduncu, Vecih | |
dc.contributor.author | Çevik, Cihan | |
dc.contributor.author | Tigen, Kürşat | |
dc.contributor.author | Şirin, Gökçe | |
dc.contributor.author | Özker, Emre | |
dc.contributor.author | Kıran, Burak | |
dc.contributor.author | Başaran, Yelda | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T19:35:30Z | |
dc.date.available | 10.07.201910:49:14 | |
dc.date.available | 2019-07-10T19:35:30Z | |
dc.date.issued | 2011 | en_US |
dc.identifier.citation | Fotbolcu, H., Duman, D., Alışır Ecder, S., Oduncu, V., Çevik, C., Tigen, K. ... Başaran, Y. (2011). Attenuated cardiovascular response to sympathetic system activation during exercise in patients with dialysis-induced hypotension. American Journal of Nephrology, 33(6), 491-498. https://dx.doi.org/10.1159/000327829 | en_US |
dc.identifier.issn | 0250-8095 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/811 | |
dc.identifier.uri | https://dx.doi.org/10.1159/000327829 | |
dc.description.abstract | Background: We wished to investigate potential causes of dialysis-induced hypotension (DIH), including the attenuated cardiovascular response to sympathetic system activation during exercise and myocardial dysfunction. Methods: This study included 26 end-stage renal disease (ESRD) patients with DIH, 30 ESRD patients without DIH (Non-DIH), and 30 control subjects. Each patient was evaluated with echocardiography and a symptom-limited treadmill stress test. The chronotropic index (CRI), heart rate recovery (HRR), systolic blood pressure response to exercise (SBP response), and tissue Doppler systolic myocardial velocities were calculated. Results: The HRR and velocities were reduced in dialysis patients compared to controls; however, they were similar in patients with and without DIH. Patients with DIH had the lowest CRI compared to theNon-DIH group (0.62 ± 0.15 vs. 0.73 ± 0.17, p = 0.020) and controls (0.62 ± 0.15 vs. 0.86 ± 0.11, p < 0.001). Similarly, patients with DIH had the lowest SBP response values compared to the Non-DIH (34.88 ± 15.01 vs. 55.67 ± 25.42, p = 0.002) and controls (34.88 ± 15.01 vs. 59.70 ± 23.04, p < 0.001). Conclusion: Patients with DIH have inadequate sympathetic activity of the cardiovascular system during exercise and impaired left ventricular systolic function. Both factors could contribute to the development of hypotension during hemodialysis. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Karger | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Autonomic Nervous System | en_US |
dc.subject | Chronotropic Incompetence | en_US |
dc.subject | Dialysis | en_US |
dc.subject | Heart Rate Recovery | en_US |
dc.subject | Hypotension | en_US |
dc.subject | Systolic Blood Pressure | en_US |
dc.title | Attenuated cardiovascular response to sympathetic system activation during exercise in patients with dialysis-induced hypotension | en_US |
dc.type | article | en_US |
dc.relation.ispartof | American Journal of Nephrology | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı | en_US |
dc.identifier.volume | 33 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 491 | en_US |
dc.identifier.endpage | 498 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1159/000327829 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.identifier.scopusquality | Q1 | en_US |