Show simple item record

dc.contributor.authorSakallıoğlu, Öner
dc.contributor.authorPolat, Cahit
dc.contributor.authorSoylu, Erkan
dc.contributor.authorDüzer, Sertaç
dc.contributor.authorOrhan, İsrafil
dc.contributor.authorAkyiğit, Abdulvahap
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:35:29Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:35:29Z
dc.date.issued2015
dc.identifier.citationSakallıoğlu, Ö., Polat, C., Soylu, E., Düzer, S., Orhan, İ. ve Akyiğit, A. (2015). The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty. Annals of Plastic Surgery, 74(4), 392-396. https://dx.doi.org/10.1097/SAP.0b013e3182a1e527en_US
dc.identifier.issn0148-7043
dc.identifier.issn1536-3708
dc.identifier.urihttps://hdl.handle.net/20.500.12511/800
dc.identifier.urihttps://dx.doi.org/10.1097/SAP.0b013e3182a1e527
dc.description.abstractThe aim of this study was to investigate the efficacy of tranexamic acid (TA) and methylprednisolone on periorbital edema, ecchymosis, and intraoperative bleeding in patients who underwent open septorhinoplasty (oSRP). Seventy-five patients performing hump extraction and osteotomies were allocated into 3 groups as follows: group 1, 25 patients as control; group 2, 25 patients who were administered oral TA as first dose 1 g starting 2 hours before surgery, 3 g daily in divided doses (1 g, every 8 hours) for 5 days; and group 3, 25 patients who were administered a single dose of 1 mg/kg intravenous methylprednisolone at the beginning of the surgery. Operation time, amount of intraoperative bleeding, and complications were recorded. Scoring of eyelid edema and periorbital ecchymosis was evaluated on postoperative first, third, and seventh days using scale of 0 to 4 by 2 observers. In groups using TA and methylprednisolone, periorbital edema and ecchymosis scores were significantly lower compared with the control group (P < 0.05). No significant difference was seen clinically and statistically in preventing or decreasing both periorbital edema and ecchymosis between group 2 and group 3. Patients given TA showed significantly less intraoperative bleeding compared with controls and patients who were administered methylprednisolone. We observed that the administration of methylprednisolone significantly decreases periorbital edema and ecchymosis. Additionally, our results support that TA use in patients who underwent oSRP with osteotomies was found clinically and statistically effective for prevention of bleeding during oSRP operations and reduction of both periorbital edema and ecchymosis.en_US
dc.language.isoengen_US
dc.publisherLippincott Williams and Wilkinsen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectEcchymosisen_US
dc.subjectEdemaen_US
dc.subjectMethylprednisoloneen_US
dc.subjectRhinoplastyen_US
dc.subjectTranexamic Aciden_US
dc.titleThe efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplastyen_US
dc.typearticleen_US
dc.relation.journalAnnals of Plastic Surgeryen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun Boğaz Hastalıkları Ana Bilim Dalıen_US
dc.identifier.volume74en_US
dc.identifier.issue4en_US
dc.identifier.startpage392en_US
dc.identifier.endpage396en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1097/SAP.0b013e3182a1e527en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record