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dc.contributor.authorÖzahi İpek, İlke
dc.contributor.authorBozaykut, Abdulkadir
dc.contributor.authorÇaktır Arman, Didem
dc.contributor.authorSezer Gönül , Rabia
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:35:28Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:35:28Z
dc.date.issued2011en_US
dc.identifier.citationÖzahi İpek, İ., Bozaykut, A., Çaktır Arman, D. ve Sezer Gönül, R. (2011). Antimicrobial resistance patterns of uropathogens among children in Istanbul, Turkey. Southeast Asian Journal of Tropical Medicine and Public Health, 42(2), 355-362.en_US
dc.identifier.issn0125-1562
dc.identifier.urihttps://hdl.handle.net/20.500.12511/792
dc.description.abstractUrinary tract infections are a common cause of end-stage renal disease in Turkey. This prospective study investigated the antibiotic resistance patterns of uropathogens in order to recommend appropriate therapeutic protocols for children with urinary tract infections in Istanbul, Turkey. Between October 2007 and October 2008, children presenting with a first episode of urinary tract infection to a pediatric outpatient clinic were enrolled in the study. Urine samples were cultured, and antimicrobial susceptibility testing was performed. Children with proven urinary tract infections underwent imaging studies where available. A total of 126 children with a first episode of community-acquired urinary tract infection were enrolled in the study. The median age was 60.6 months; 84.1% of the children were female. Of the 126 urine samples, Escherichia coli was the leading uropathogen (81.7%), followed by Proteus spp (7.1%), Klebsiella spp (4.0%), Enterococcus spp (3.2%), Enterobacter spp (2.4%), and Pseudomonas spp (1.6%). Among the isolated uropathogens, resistance to ampicillin (85.0%), amoxicillin-clavulanate (73.8%), cefazolin (37.3%) and trimethoprim-sulfamethoxazole (42.9%) was remarkable. A large number of Enterococcus species were resistant to all antimicrobial agents except vancomycin. A country-based evaluation of antibiotic susceptibility is needed to modify antibiotic treatment. Resistance to antimicrobial agents commonly used to treat urinary tract infections (nitrofurantoin, cefixime) is less a problem than resistance to other antimicrobials (aminopenicillins, cephalosporins, trimethoprim-sulfamethoxazole) frequently prescribed for other indications.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntibiotic Resistanceen_US
dc.subjectChildrenen_US
dc.subjectTurkeyen_US
dc.subjectUropathogensen_US
dc.titleAntimicrobial resistance patterns of uropathogens among children in Istanbul, Turkeyen_US
dc.typearticleen_US
dc.relation.ispartofSoutheast Asian Journal of Tropical Medicine and Public Healthen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.identifier.volume42en_US
dc.identifier.issue2en_US
dc.identifier.startpage355en_US
dc.identifier.endpage362en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.wosqualityQ4en_US
dc.identifier.scopusqualityQ3en_US


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