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dc.contributor.authorAkkoyunlu, Yasemin
dc.contributor.authorKalaycıoğlu, Bora
dc.contributor.authorYurtsever, İsmail
dc.contributor.authorEren, Abdulkadir
dc.contributor.authorBayram, Merve
dc.contributor.authorMert, Ali
dc.contributor.authorAkkoyunlu, Muhammed Emin
dc.date.accessioned2021-07-02T09:39:45Z
dc.date.available2021-07-02T09:39:45Z
dc.date.issued2021en_US
dc.identifier.citationAkkoyunlu, Y., Kalaycıoğlu, B., Yurtsever, İ., Eren, A., Bayram, M., Mert, A. ... Akkoyunlu, M. E. (2021). Analysis of the involvement of the thyroid gland using computed tomography in patients with suspected SARS-CoV-2 infection: A retrospective study. European Review for Medical and Pharmacological Sciences, 25(11), 4149-4155. https://dx.doi.org/10.26355/eurrev_202106_26058en_US
dc.identifier.issn1128-3602
dc.identifier.urihttps://dx.doi.org/10.26355/eurrev_202106_26058
dc.identifier.urihttps://hdl.handle.net/20.500.12511/7433
dc.description.abstractOBJECTIVE: SARS-CoV-2 primarily infects the respiratory tract and leads to severe pneumonia by binding to the ACE-2 receptor. The virus can also interact with ACE-2 receptors expressed in other tissues as in thyroid. This study predicted the complications involving the thyroid in patients with suspected SA RS-CoV-2. PATIENTS AND METHODS: Patients with suspected SARS-CoV-2 infection between March 11, 2020-May 31, 2020 were retrospectively evaluated. Sixty-nine patients who were radiologically diagnosed as COVID-19 according to thoracic CT and had previously performed thoracic CT before November 2019 were included in the study according to the exclusion and inclusion criteria. Age and gender-matched controls (No. 69) were selected with normal thoracic CT whose PCR tests were also negative. Thyroid densities of participants were calculated and compared from the previous and current thoracic CTs. Results were also compared with the control group. RESULTS: Participants were composed of 69 patients (39 male, mean age 64.35 years). Thyroid densities were significantly decreased from 89HU to 76HU for whole gland, from 88HU to 76HU for right lobes and from 87.5HU to 75.5HU for left lobes at current thoracic CTs performed during COVID-19 (p<0.001, p<0.001, p<0.001 respectively). The decrease in densities of the whole thyroid gland. both left and right lobes. was correlated with mortality (p<0.001). The changes in thyroid densities were not correlated with age nor gender. The decreases in HU values of thyroid densities for whole gland, left and right lobes, were correlated with mortality (p<0.001, p<0.001. and p<0.001 respectively). CONCLUSIONS: COVID-19 is a multi-systemic disease that threatens vital organs, including the thyroid. Future studies are needed to investigate the association between SARS-CoV-2 and other complications.en_US
dc.language.isoengen_US
dc.publisherVerduci Editore s.r.len_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectSARS-CoV-2en_US
dc.subjectThyroiden_US
dc.subjectComputed Tomographyen_US
dc.subjectCOVID-19en_US
dc.titleAnalysis of the involvement of the thyroid gland using computed tomography in patients with suspected SARS-CoV-2 infection: A retrospective studyen_US
dc.typearticleen_US
dc.relation.journalEuropean Review for Medical and Pharmacological Sciencesen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalıen_US
dc.authorid0000-0002-8440-367Xen_US
dc.authorid0000-0001-8945-2385en_US
dc.identifier.volume25en_US
dc.identifier.issue11en_US
dc.identifier.startpage4149en_US
dc.identifier.endpage4155en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.26355/eurrev_202106_26058en_US


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