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dc.contributor.authorDuman, Dursun
dc.date.accessioned08.07.201910:49:13
dc.date.accessioned2019-07-08T20:19:28Z
dc.date.available08.07.201910:49:13
dc.date.available2019-07-08T20:19:28Z
dc.date.issued2012en_US
dc.identifier.citationDuman, D. (2012). Is increased epicardial fat thickness a marker of the presence of severe coronary artery disease? The Anatolian Journal of Cardiology, 12(3), 206-207. https://dx.doi.org/10.5152/akd.2012.062en_US
dc.identifier.issn1302-8723
dc.identifier.urihttps://hdl.handle.net/20.500.12511/727
dc.identifier.urihttps://dx.doi.org/10.5152/akd.2012.062
dc.description.abstractFat is mainly deposited in subcutaneous tissue, but it also accumulates in the abdominal or thoracal region (1). Other major sites of fat accumulation are visceral and cardiac areas; Cardiac fat deposition is now recognized as a new cardiometabolic risk marker, as it is associated with increased insulin resistance, cardiovascular risk factors, as their measurement is practical (2). Fat accumulation in the heart appears in three different types: intracellular, epicardial and pericardial. Intracellular fat is the microscopic lipid accumulation within the cytoplasm of cardiac muscle and can be the result of myocardial ischemia, cell damage or cell death. Epicardial fat is located between the outer wall of the myocardium and the visceral layer of pericardium (3). Pericardial fat exists anterior to the epicardial fat layer and therefore located between visceral and parietal pericardium. Due to the close anatomic relation between myocardium and the epicardial fat, the two tissues share the same microcirculation (4). In previous studies have been reported that epicardial fat is metabolically active and is the source for several adipokines. Potential interactions through paracrine or vasocrine mechanisms between epicardial fat and myocardium are strongly suggested (4).en_US
dc.language.isoengen_US
dc.publisherAVESen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectEpicardial Fat Thicknessen_US
dc.subjectKoroner Arter Hastalığıen_US
dc.subjectEpikardiyal Yağ Kalınlığıen_US
dc.titleIs increased epicardial fat thickness a marker of the presence of severe coronary artery disease?en_US
dc.title.alternativeEpikardiyal yağ kalınlığının artışı şiddetli koroner arter hastalığı varlığının bir belirteci midir?en_US
dc.typeeditorialen_US
dc.relation.journalThe Anatolian Journal of Cardiologyen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.identifier.volume12en_US
dc.identifier.issue3en_US
dc.identifier.startpage206en_US
dc.identifier.endpage207en_US
dc.relation.publicationcategoryDiğeren_US
dc.identifier.doi10.5152/akd.2012.062en_US


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