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dc.contributor.authorUzun, Kübra Nur
dc.contributor.authorCıncık, Mehmet
dc.contributor.authorSelam, Belgin
dc.contributor.authorTakmaz, Özgüç
dc.contributor.authorUyar, Esra
dc.date.accessioned2021-06-17T06:24:38Z
dc.date.available2021-06-17T06:24:38Z
dc.date.issued2021en_US
dc.identifier.citationUzun, K. N., Cıncık, M., Selam, B., Takmaz, Ö. ve Uyar, E. (2021). Comparison of the rates for reaching the blastocyst stage between normal and abnormal pronucleus embryos monitored by a time-lapse system in IVF patients. Journal of the Turkish-German Gynecological Association, 22(2), 120-126. https://dx.doi.org/10.4274/jtgga.galenos.2021.2020.0033en_US
dc.identifier.issn1309-0399
dc.identifier.issn1309-0380
dc.identifier.urihttps://dx.doi.org/10.4274/jtgga.galenos.2021.2020.0033
dc.identifier.urihttps://hdl.handle.net/20.500.12511/7204
dc.description.abstractObjective: To compare the rates of blastocyst stage development between embryos fertilized after one (MPN) or more than two pronucleus (PN) (3PN, 4PN-multiPN) with those after 2PN in the same patients. Material and Methods: The embryos of patients who had both abnormal PN (MPN, 3PN or 4PN) and normal fertilized (2PN) embryos after intracytoplasmic sperm injection (ICSI) fertilization, were followed with a time-lapse system following the ICSI procedure. The rates of reaching the blastocyst stage were compared between normal and abnormally fertilized embryos. Results: One thousand eight hundred and twenty oocytes were collected from 140 patients and 1280 (70.3%) of them were fertilized. MPN, 2PN and 3PN, 4PN (multiPN) ratios of the embryos in the pronuclear stage were 11.4%, 83.13% and 5.47%, respectively. The rates of reaching the blastocyst stage among these embryos were 17.1%, 60.8% and 42.8% for MPN, 2PN and multiPN, respectively. The proportion reaching blastocyst development was significantly higher following 2PN compared to those after MPN and multiPN (p<0.05). Embryos developing after multiPN had significantly higher rates of reaching the blastocyst stage compared to those after MPN (p<0.01). Conclusion: The majority of abnormally pronucleated embryos arrest without reaching the blastocyst stage. MultiPN embryos have a higher rate of blastocyst development than MPN embryos.en_US
dc.language.isoengen_US
dc.publisherGalenos Yayıncılıken_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBlastocysten_US
dc.subjectICSIen_US
dc.subjectMPNen_US
dc.subjectmultiPNen_US
dc.subjectTime-Lapseen_US
dc.titleComparison of the rates for reaching the blastocyst stage between normal and abnormal pronucleus embryos monitored by a time-lapse system in IVF patientsen_US
dc.typearticleen_US
dc.relation.ispartofJournal of the Turkish-German Gynecological Associationen_US
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, Histoloji ve Embriyoloji Ana Bilim Dalıen_US
dc.authorid0000-0001-6440-0984en_US
dc.identifier.volume22en_US
dc.identifier.issue2en_US
dc.identifier.startpage120en_US
dc.identifier.endpage126en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - İdari Personel ve Öğrencien_US
dc.identifier.doi10.4274/jtgga.galenos.2021.2020.0033en_US
dc.identifier.scopusqualityQ3en_US


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