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dc.contributor.authorTolu, Sena
dc.contributor.authorKöse, Muammer Müslim
dc.contributor.authorÇalkın Korkmaz, Merve
dc.contributor.authorÜşen, Ahmet
dc.contributor.authorRezvani, Aylin
dc.date.accessioned2021-06-03T07:55:28Z
dc.date.available2021-06-03T07:55:28Z
dc.date.issued2021en_US
dc.identifier.citationTolu, S., Köse, Muammer M., Çalkın Korkmaz, M., Üşen, A. ve Rezvani, A. (2021). Comparison of the efficacy of different concentrations of diclofenac sodium phonophoresis (1.16% vs 2.32%) in patients with knee osteoarthritis: A randomized double -blind controlled trial. Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca, 88(2), 117-123.en_US
dc.identifier.issn0001-5415
dc.identifier.urihttps://hdl.handle.net/20.500.12511/7019
dc.description.abstractPURPOSE OF THE STUDY The objective of the present study is to compare the efficacy of two different concentrations of diclofenac sodium phonophoresis (DSPH) (1.16% vs 2.32%) in patients with knee osteoarthritis (OA). MATERIAL AND METHODS A randomized, double-blind, controlled design was applied. Ninety patients (mean age SD, 59.98 8.89 years) who had Kellgren-Lawrence (K-L) grades II to III knee OA were randomly allocated into three groups; 1.16% DSPH, 2.32% DSPH, TUS (30 in each group). Each patient was treated five sessions per week for two weeks. A 100-mm visual analogue scale (VAS) for usual pain and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were evaluated before and after treatment in all groups. RESULTS The VAS pain and WOMAC scores were significantly improved after treatment in all groups (p < 0.05). The 2.32% DSPH showed more significant effects than the 1.16% DSPH, both in improving WOMAC- pain and physical function scores (p = 0.020, p = 0.008) and reducing the VAS pain measure, although it did not reach the level of significance (p = 0.077). The 2.32% DSPH was superior to the TUS, both in reducing the VAS pain measure (p < 0.001) and in improving WOMAC-pain, stiffness, physical function and total scores (p = 0.022, p = 0.016, p < 0.001, p < 0.001 respectively). 1.16% DSPH significantly reduced stiffness and physical function scores compared with TUS (p = 0.042, p = 0.047). CONCLUSIONS DSPH and TUS are effective treatments for knee OA. Our results indicated that 2.32% DSPH produces additional benefits to functional improvement and pain reduction compared with 1.16% DSPH in K-L grades II to III knee OA.en_US
dc.language.isoengen_US
dc.publisherGalen S.R.O.en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiclofenac Sodiumen_US
dc.subjectKnee Osteoarthritisen_US
dc.subjectPhonophoresisen_US
dc.subjectTherapeutic Ultrasounden_US
dc.subjectTopical Formulationen_US
dc.titleComparison of the efficacy of different concentrations of diclofenac sodium phonophoresis (1.16% vs 2.32%) in patients with knee osteoarthritis: A randomized double -blind controlled trialen_US
dc.typearticleen_US
dc.relation.journalActa Chirurgiae Orthopaedicae et Traumatologiae Cechoslovacaen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalıen_US
dc.authorid0000-0002-1111-3110en_US
dc.authorid0000-0002-5852-3854en_US
dc.identifier.volume88en_US
dc.identifier.issue2en_US
dc.identifier.startpage117en_US
dc.identifier.endpage123en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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