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dc.contributor.authorHeydari, Hajar
dc.contributor.authorKonuklugil, Belma
dc.contributor.authorGiray, Betül
dc.contributor.authorKaradağ, Ayşe Esra
dc.contributor.authorGüzel, Mustafa
dc.date.accessioned2021-02-19T11:42:19Z
dc.date.available2021-02-19T11:42:19Z
dc.date.issued2020en_US
dc.identifier.citationHeydari, H., Konuklugil, B., Giray, B., Karadağ, A. E. ve Güzel, M. (2020). Identification and in vitro bioactivity screening of some marine-derived fungi from Turkish coastlines. Cahiers de Biologie Marine, 61(5), 437-446. https://dx.doi.org/10.21411/CBM.A.A3EE9FBen_US
dc.identifier.issn0007-9723
dc.identifier.issn2262-3094
dc.identifier.urihttps://dx.doi.org/10.21411/CBM.A.A3EE9FB
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6570
dc.description.abstractThe marine environment represents a great variety of conditions of pressure, temperature, salinity, and light depending on depth, latitude and interactions with the continental shelf. These extreme and variable conditions enforce marine-derived microbial communities to produce a variety of structurally complex secondary metabolites which may have considerable pharmaceutical potential. In this study four marine-derived fungi were successfully isolated and identified from marine invertebrates (Axinella cannabina, Aplysina aerophoba, Axinella verrucosa, Dendrectilla tremitersis) and investigated for their antioxidant, cytotoxic, antifungal and antimicrobial activities. Three marine fungi strains - Aspergillus sp., Trichoderma sp. and Rhizopus oryzae - were isolated and identified genotypically. Aspergillus sp. had the highest antioxidant activity, and together with Rhizopus oryzae also showed significant cytotoxic activity against HCT-116 cell line. Moreover, among the tested marine-derived fungi extracts Aspergillus sp. was exhibited the highest antifungal activity against Botrytis cinerea.en_US
dc.language.isoengen_US
dc.publisherCahiers de Biologie Marineen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidanten_US
dc.subjectAntifungalen_US
dc.subjectAntimicrobial Activitiesen_US
dc.subjectCytotoxicityen_US
dc.subjectMarine Derived-Fungien_US
dc.titleIdentification and in vitro bioactivity screening of some marine-derived fungi from Turkish coastlinesen_US
dc.typearticleen_US
dc.relation.journalCahiers de Biologie Marineen_US
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakognozi Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümü, Farmasötik Mikrobiyoloji Ana Bilim Dalıen_US
dc.authorid0000-0003-1318-6476en_US
dc.authorid0000-0002-3412-0807en_US
dc.identifier.volume61en_US
dc.identifier.issue5en_US
dc.identifier.startpage437en_US
dc.identifier.endpage446en_US
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/BMBF-114S916
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.21411/CBM.A.A3EE9FBen_US


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