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dc.contributor.authorYorulmaz, İlknur Suidiye
dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorÖzlü, Onur
dc.contributor.authorDost, Burhan
dc.date.accessioned2021-01-27T12:05:53Z
dc.date.available2021-01-27T12:05:53Z
dc.date.issued2020en_US
dc.identifier.citationYorulmaz, İ. S., Demiraran, Y., Özlü, O. ve Dost, B. (2020). The effect of vitamin D status on different neuromuscular blocker agents reverse time. Turkish Journal of Medical Sciences, 50(4), 749-755. https://dx.doi.org/10.3906/sag-1901-115en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.urihttps://dx.doi.org/10.3906/sag-1901-115
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6419
dc.description.abstractBackground/aim: This study is aimed to investigate the effects of vitamin D levels on sugammadex and neostigmine reversal times. Material and methods: Eighty patients between the ages of 18 and 65 years, with ASA I-III status who were undergoing surgery under general anesthesia were included in the study. A double blind fashion was used to randomly divide all the patients into two groups. At the end of the operation, sugammadex 2 mg/kg was administered to one group (Group sugammadex) and atropine and neostigmine was administered to the other group (Group neostigmine) intravenously. In the data analysis stage, the group was divided into two subgroups according to sugammadex and group neostigmine in itself, with vitamin D levels above and below 30 ng/mL. Statistical analysis was performed on these 4 groups (Group neostigmine and vitamin D < 30 ng/mL), (Group neostigmine and vitamin D ≥ 30 ng/mL), (Group sugammadex and vitamin D < 30 ng/mL), (Group sugammadex and vitamin D ≥ 30 ng/mL). When two responses to train of four (TOF) stimulation were taken, the following times were recorded until extubation phase. The time until TOF value 50%, 70%, 90%, and extubation were recorded. Results: There were statistically significant differences between Group sugammadex and vitamin D < 30 ng/mL and Group sugammadex and vitamin D ≥ 30 ng/mL (P = 0.007) for extubation times and 50% TOF reach times (P = 0.015). However, there was no difference observed between Group neostigmine and vitamin D < 30 ng/mL and Group neostigmine and vitamin D ≥ 30 ng/mL (P = 0.999). Conclusion: Vitamin D deficiency is important for anesthesiologists in terms of muscle strength and extubation time. Vitamin D deficiency seems to affect sugammadex reverse times but seems not to affect neostigmine reverse times. This conclusion needs further studies.en_US
dc.description.sponsorshipDüzce Üniversitesien_US
dc.language.isoengen_US
dc.publisherTürkiye Kliniklerien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAnaesthesiaen_US
dc.subjectNeostigmineen_US
dc.subjectSugammadexen_US
dc.subjectVitamin Den_US
dc.subjectMuscle Relaxationen_US
dc.subjectNeuromuscular Blockeren_US
dc.titleThe effect of vitamin D status on different neuromuscular blocker agents reverse timeen_US
dc.typearticleen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalıen_US
dc.authorid0000-0003-0811-4945en_US
dc.identifier.volume50en_US
dc.identifier.issue4en_US
dc.identifier.startpage749en_US
dc.identifier.endpage755en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.3906/sag-1901-115en_US
dc.identifier.wosqualityQ4en_US
dc.identifier.scopusqualityQ3en_US


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