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dc.contributor.authorAygün, İrfan
dc.contributor.authorKaya, Mehmet
dc.contributor.authorAlhajj, Reda S.
dc.date.accessioned2021-01-08T05:46:00Z
dc.date.available2021-01-08T05:46:00Z
dc.date.issued2020en_US
dc.identifier.citationAygün, İ., Kaya, M. ve Alhajj, R. S. (2020). Identifying side effects of commonly used drugs in the treatment of Covid 19. Scientific Reports, 10(1). https://dx.doi.org/10.1038/s41598-020-78697-1en_US
dc.identifier.issn2045-2322
dc.identifier.urihttps://dx.doi.org/10.1038/s41598-020-78697-1
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6203
dc.description.abstractTo increase the success in Covid 19 treatment, many drug suggestions are presented, and some clinical studies are shared in the literature. There have been some attempts to use some of these drugs in combination. However, using more than one drug together may cause serious side effects on patients. Therefore, detecting drug-drug interactions of the drugs used will be of great importance in the treatment of Covid 19. In this study, the interactions of 8 drugs used for Covid 19 treatment with 645 different drugs and possible side effects estimates have been produced using Graph Convolutional Networks. As a result of the experiments, it has been found that the hematopoietic system and the cardiovascular system are exposed to more side effects than other organs. Among the focused drugs, Heparin and Atazanavir appear to cause more adverse reactions than other drugs. In addition, as it is known that some of these 8 drugs are used together in Covid-19 treatment, the side effects caused by using these drugs together are shared. With the experimental results obtained, it is aimed to facilitate the selection of the drugs and increase the success of Covid 19 treatment according to the targeted patient.en_US
dc.language.isoengen_US
dc.publisherNature Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectCovid 19en_US
dc.subjectDrugsen_US
dc.subjectTreatmenten_US
dc.titleIdentifying side effects of commonly used drugs in the treatment of Covid 19en_US
dc.typearticleen_US
dc.relation.ispartofScientific Reportsen_US
dc.departmentİstanbul Medipol Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Bilgisayar Mühendisliği Bölümüen_US
dc.authorid0000-0001-6657-9738en_US
dc.identifier.volume10en_US
dc.identifier.issue1en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1038/s41598-020-78697-1en_US
dc.identifier.wosqualityQ1en_US
dc.identifier.scopusqualityQ1en_US


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