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dc.contributor.authorKutluhan, Musab Ali
dc.contributor.authorTaş, Ahmet
dc.contributor.authorŞahin, Aytaç
dc.contributor.authorÜrkmez, Ahmet
dc.contributor.authorTopaktaş, Ramazan
dc.contributor.authorAtaç, Ömer
dc.contributor.authorVerit, Ayhan
dc.date.accessioned2020-12-28T07:11:25Z
dc.date.available2020-12-28T07:11:25Z
dc.date.issued2020en_US
dc.identifier.citationKutluhan, M. A., Taş, A., Şahin, A., Ürkmez, A., Topaktaş, R., Ataç, Ö. ... Verit, A. (2020). Assessment of clinical features and renal functions in Coronavirus disease-19: A retrospective analysis of 96 patients. International Journal of Clinical Practice, 74(12). https://dx.doi.org/10.1111/ijcp.13636en_US
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.urihttps://dx.doi.org/10.1111/ijcp.13636
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6153
dc.description.abstractBackground The most common extra pulmonary organ dysfunction in acute respiratory distress syndrome is acute kidney injury. Current data so far indicate low incidence of AKI in Covid-19 disease. Objective In this retrospective study, we analysed the clinical features of patients diagnosed with Covid-19 and investigated the effect of Covid-19 on kidney function. Methods Ninety-six patients diagnosed with Covid-19 were included in our study. Demographic features (Age, gender, co-morbidities), symptoms, thorax CT findings, Covid-19 PCR results and laboratory findings were recorded. The clinical features of the patients were analysed and kidney function values before Covid-19 diagnosis were compared with kidney function values after Covid-19 diagnosis. Results Most presenting symptom was fever (51%). Most accompanying co-morbidity was hypertension (56%). According to laboratory findings; ferritin, D-dimer and C-reactive protein levels were statistically significantly higher in ARDS group than severe pneumonia and pneumonia group (P = .002,P = .001 andP < .001, respectively). Also lymphocyte levels were statistically significantly lower in ARDS group than severe pneumonia and pneumonia group (P = .042). According to KDIGO criteria 3 (3.1%) patients had AKI during the hospital stay. For all patients, there was statistically significant difference between basal, 1st, 5th and 10th day BUN and SCr levels (P = .024 andP = .018, respectively). For severe pneumonia group there was statistically significant difference between basal, 1st, 5th and 10th day SCr levels (P = .045). Conclusion Our study demonstrated that Covid-19 can cause renal impairment both with pneumonia and ARDS. A large-scale prospective randomised studies are needed to reach final judgement about this topic.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronavirus Disease-19en_US
dc.subjectCOVID-19en_US
dc.subjectRenal Functionsen_US
dc.titleAssessment of clinical features and renal functions in Coronavirus disease-19: A retrospective analysis of 96 patientsen_US
dc.typearticleen_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Halk Sağlığı Ana Bilim Dalıen_US
dc.authorid0000-0001-8984-9673en_US
dc.identifier.volume74en_US
dc.identifier.issue12en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1111/ijcp.13636en_US
dc.identifier.wosqualityQ2en_US
dc.identifier.scopusqualityQ2en_US


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