dc.contributor.author | Kutluhan, Musab Ali | |
dc.contributor.author | Taş, Ahmet | |
dc.contributor.author | Şahin, Aytaç | |
dc.contributor.author | Ürkmez, Ahmet | |
dc.contributor.author | Topaktaş, Ramazan | |
dc.contributor.author | Ataç, Ömer | |
dc.contributor.author | Verit, Ayhan | |
dc.date.accessioned | 2020-12-28T07:11:25Z | |
dc.date.available | 2020-12-28T07:11:25Z | |
dc.date.issued | 2020 | en_US |
dc.identifier.citation | Kutluhan, M. A., Taş, A., Şahin, A., Ürkmez, A., Topaktaş, R., Ataç, Ö. ... Verit, A. (2020). Assessment of clinical features and renal functions in Coronavirus disease-19: A retrospective analysis of 96 patients. International Journal of Clinical Practice, 74(12). https://dx.doi.org/10.1111/ijcp.13636 | en_US |
dc.identifier.issn | 1368-5031 | |
dc.identifier.issn | 1742-1241 | |
dc.identifier.uri | https://dx.doi.org/10.1111/ijcp.13636 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/6153 | |
dc.description.abstract | Background The most common extra pulmonary organ dysfunction in acute respiratory distress syndrome is acute kidney injury. Current data so far indicate low incidence of AKI in Covid-19 disease. Objective In this retrospective study, we analysed the clinical features of patients diagnosed with Covid-19 and investigated the effect of Covid-19 on kidney function. Methods Ninety-six patients diagnosed with Covid-19 were included in our study. Demographic features (Age, gender, co-morbidities), symptoms, thorax CT findings, Covid-19 PCR results and laboratory findings were recorded. The clinical features of the patients were analysed and kidney function values before Covid-19 diagnosis were compared with kidney function values after Covid-19 diagnosis. Results Most presenting symptom was fever (51%). Most accompanying co-morbidity was hypertension (56%). According to laboratory findings; ferritin, D-dimer and C-reactive protein levels were statistically significantly higher in ARDS group than severe pneumonia and pneumonia group (P = .002,P = .001 andP < .001, respectively). Also lymphocyte levels were statistically significantly lower in ARDS group than severe pneumonia and pneumonia group (P = .042). According to KDIGO criteria 3 (3.1%) patients had AKI during the hospital stay. For all patients, there was statistically significant difference between basal, 1st, 5th and 10th day BUN and SCr levels (P = .024 andP = .018, respectively). For severe pneumonia group there was statistically significant difference between basal, 1st, 5th and 10th day SCr levels (P = .045). Conclusion Our study demonstrated that Covid-19 can cause renal impairment both with pneumonia and ARDS. A large-scale prospective randomised studies are needed to reach final judgement about this topic. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Coronavirus Disease-19 | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Renal Functions | en_US |
dc.title | Assessment of clinical features and renal functions in Coronavirus disease-19: A retrospective analysis of 96 patients | en_US |
dc.type | article | en_US |
dc.relation.ispartof | International Journal of Clinical Practice | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Halk Sağlığı Ana Bilim Dalı | en_US |
dc.authorid | 0000-0001-8984-9673 | en_US |
dc.identifier.volume | 74 | en_US |
dc.identifier.issue | 12 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1111/ijcp.13636 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.identifier.scopusquality | Q2 | en_US |