Başlık için Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü (SABİTA) listeleme
Toplam kayıt 208, listelenen: 23-42
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Cannabidiol as a potential novel treatment for endometriosis by its anti-inflammatory, antioxidative and antiangiogenic effects in an experimental rat model
(Elsevier Science Ltd, 2023)Research question: Can cannabidiol (CBD) be used in the treatment of endometriosis for its anti-inflammatory, antioxidative and antiangiogenic effects? Design: Endometrial implants were surgically induced in 36 female ... -
Cardiac immunology: A new era for immune cells in the heart
(Plenum Press, 2021)The immune system is essential for the development and homeostasis of the human body. Our current understanding of the immune system on disease pathogenesis has drastically expanded over the last decade with the definition ... -
Centralized healthcare database for ensuring better healthcare: Are we lagging behind?
(Professional Medical Publications, 2024)Database is an organized set of large information gathered and stored electronically to be retrieved whenever required. The systematically stored information can be ... -
Characterization of FcγRIa (CD64) as a ligand molecule for site-specific IgG1 capture: A side-by-side comparison with protein a
(American Chemical Society, 2022)Fc γreceptors (FcγRs) are one of the structures that can initiate effector function for monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal antibodies among all FcγRs. In this study, a ... -
Chemo-mechanical processing of hot chamber die cast scrap to design ZnO-based composite anode for lithium-ion batteries
(Elsevier Ltd, 2024)Zn–4Al alloy is mostly processed via high pressure, hot chamber die-casting method. For the first time in the open literature, in this study a novel and useful advice regarding the valorization of zinc die-cast scrap in ... -
Chemogenetic approaches to dissect the role of H2O2 in redox-dependent pathways using genetically encoded biosensors
(Portland Press Ltd, 2022)Chemogenetic tools are recombinant enzymes that can be targeted to specific organelles and tissues. The provision or removal of the enzyme substrate permits control of its biochemical activities. Yeast-derived enzyme D-amino ... -
Chemogenetic inhibition of MCH neurons does not alter memory performance in mice
(Elsevier Masson s.r.l., 2022)Memory storage in the brain is one of the most extensively studied subjects in neuroscience. However, due to the highly complex structure of the memory-related systems in the brain, the mystery remains unsolved. Consolidation ... -
Chemogenetic tools and genetic biosensors in redox biology: Probing Hyper7 signals in specific cellular locales
(Elsevier Science Inc., 2023)H2O2 is one of the most studied reactive oxygen species (ROS) in redox biology because of its critical role in oxidant-dependent signaling pathways. Conventional approaches apply exogenous H2O2 on cells and tissues, which ... -
Chronic unpredictable stress disturbs the blood-testis barrier affecting sperm parameters in mice
(Elsevier Ltd, 2021)Research question: Does chronic stress affect the key proteins and sperm parameters of the blood & ndash;testis barrier (BTB)? Design: C57Bl/6 mice were divided into two groups: a non-treated control group and a chronic ... -
Classification of Parkinson's disease with dementia using phase locking factor of event-related oscillations to visual and auditory stimuli
(IOP Publishing Ltd, 2023)Objective. In the last decades, machine learning approaches have been widely used to distinguish Parkinson’s disease (PD) and many other neuropsychiatric diseases. They also speed up the clinicians and facilitate decision-making ... -
Clinical evaluation and resting state fMRI analysis of virtual reality based training in Parkinson's disease through a randomized controlled trial
(Nature Research, 2022)There are few studies investigating the short-term effects of Virtual Reality based Exergaming (EG) on motor and cognition simultaneously and pursue the brain functional activity changes after these interventions in patients ... -
A co-culture-based multiparametric imaging technique to dissect local H2O2 signals with targeted HyPer7
(MDPI, 2021)Multispectral live-cell imaging is an informative approach that permits detecting biological processes simultaneously in the spatial and temporal domain by exploiting spectrally distinct biosensors. However, the combination ... -
Combined segmentation and classificationbased approach to automated analysis of biomedical signals obtained from calcium imaging
(Public Library of Science, 2023)Automated screening systems in conjunction with machine learning-based methods are becoming an essential part of the healthcare systems for assisting in disease diagnosis. Moreover, manually annotating data and hand-crafting ... -
Comparison of S gene mutations in patients with occult and chronic hepatitis B virus infection
(Elsevier B.V., 2022)Background and aim: This study aimed to detect mutations in the HBV S gene and evaluate their relationship to occult hepatitis B virus (HBV) infection (OBI). Methods: The study included 32 patients with negative serum HBsAg ... -
Complexities of the chemogenetic toolkit: Differential mDAAO activation by D-amino substrates and subcellular targeting
(Elsevier Inc., 2021)A common approach to investigate oxidant-regulated intracellular pathways is to add exogenous H2O2 to living cells or tissues. However, the addition of H2O2 to the culture medium of cells or tissues approach does not ... -
Corrosion behavior of Ni–Fe–Mo deposits obtained under different electrodeposition conditions
(Springer, 2021)Ternary Ni-Fe-Mo coatings have been proposed for anti-corrosion applications to replace chromium coating. To analyze the effects of deposition current and duration six different Ni-Fe-Mo films have been electrodeposited ... -
Culturing, freezing, processing, and imaging of entire organoids and spheroids while still in a hydrogel
(Journal of Visualized Experiments, 2022)Organoids and spheroids, three-dimensional growing structures in cell culture labs, are becoming increasingly recognized as superior models compared to two-dimensional culture models, since they mimic the human body better ... -
Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines
(MDPI, 2022)To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell ... -
Data-driven medicine: The promise and potential of clinical decision support systems
(University of Faisalabad, 2024)Patient safety is one of the most important factors involved in any health care policy. The idea of evidence-based medicine has emerged as the dominant paradigm in clinical practice, influencing our current understanding ... -
Defining optimal enzyme and matrix combination for replating of human induced pluripotent stem cell-derived cardiomyocytes at different levels of maturity
(Elsevier Inc., 2021)Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) create an unlimited cell source for basic and translational research. Depending on the maturity of cardiac cultures and the intended applications, ...
