Kurum Yazarı "Güzel, Mustafa" Enstitüler İçin Listeleme
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Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines
Aydın, Esranur; Şentürk, Ahmet Mesut; Başpınar Küçük, Hatice; Güzel, Mustafa (MDPI, 2022)To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell ... -
Design and synthesis of novel caffeic acid phenethyl ester (CAPE) derivatives and their biological activity studies in glioblastoma multiforme (GBM) cancer cell lines
Onur Sucu, Bilgesu; Koç, Elif Beyza; Şavluğ İpek, Özgecan; Mirat, Afranur; Almas, Furkan; Güzel, Melike Aybala; Doğan, Berna; Uludağ, Damla; Karakaş, Nihal; Durdağı, Serdar; Güzel, Mustafa (Elsevier Inc., 2022)Glioblastoma Multiforme (GBM) is the most aggressive brain tumor and classified as one of the deadliest cancers. The current treatment plans for GBM remains to be ineffective because of its rapid progress and inability of ... -
An economical and practical procedure of favipiravir synthesis for the treatment of Covid-19
Karataş, Hacer; Hanashalshahaby, Essam Hamied Ahmed; Çatal, Ünal; Bütün, Yaşar Enes; Kurt, Elif; Gürsel, Şahin; Kaya, Adil; Güzel, Mustafa (Springer Science and Business Media Deutschland GmbH, 2023)Favipiravir is a wide-spectrum antiviral generic drug that has received large attention during the recent COVID-19 pandemic. While there are synthetic strategies for favipiravir synthesis, economical procedures could ... -
The effects of increased glucose level and glycolysis on SARS CoV-2 infection
Zurnacı, Fatma Özlem; Güzel, Mustafa (Bentham Science Publishers, 2022)COVID-19 has entered our lives as an infection with high mortality rates. Although the vaccination process has provided benefits, the death toll remains frightening worldwide. Therefore, drugs and combined therapies that ... -
Lamotrigine derivatives-synthesis, anti-cancer, and anti-MDR-bacterial activities
Khan, Mahroza Kanwal; Siddiqui, Hina; Sharif, Ruby; Güzel, Mustafa; Wahab, Atia-tul; Yousuf, Sammer; Choudhary, M. Iqbal (Elsevier B.V., 2022)A new series of quaternary ammonium salts 3–21 of lamotrigine (6-(2, 3-dichlorophenyl)-1, 2, 4-triazine-3, 5-diamine) was synthesized via N-alkylation of lamotrigine using different benzyl bromides. The new analogues were ...