Basit öğe kaydını göster

dc.contributor.authorPolat, Burcu
dc.contributor.authorHelvacı Yılmaz, Nesrin
dc.contributor.authorMantar, Nagihan
dc.contributor.authorÇadırcı, Fadime
dc.contributor.authorSitrava, Sevilay
dc.contributor.authorOzmansur, Elif Nurdan
dc.contributor.authorUzan, Mustafa
dc.contributor.authorÖzkara, Çiğdem
dc.contributor.authorHanoǧlu, Lütfü
dc.date.accessioned2020-04-16T09:53:32Z
dc.date.available2020-04-16T09:53:32Z
dc.date.issued2020en_US
dc.identifier.citationPolat, B., Helvacı Yılmaz, N., Mantar, N., Çadırcı, F., Sitrava, S., Ozmansur, E. N. ... Hanoǧlu, L. (2020). Accelerated long-term forgetting after amygdalohippocampectomy in temporal lobe epilepsy. Journal of Clinical Neuroscience, 72, 43-49. https://dx.doi.org/10.1016/j.jocn.2020.01.038en_US
dc.identifier.issn0967-5868
dc.identifier.issn1532-2653
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5132
dc.identifier.urihttps://dx.doi.org/10.1016/j.jocn.2020.01.038
dc.description.abstractAim of the study: Temporal lobe epilepsy (TLE) has been associated with the phenomenon of accelerated long-term forgetting (ALF). In this study, we aimed to demonstrate the effect of surgery on the ALF phenomena thus contributing to potential explanation of the causal mechanism.Materials and methods: We evaluated 51 patients with TLE related to hippocampal sclerosis who had amygdalohippocampectomy and had remained seizure-free after surgery. A control group consisted of 24 healthy individuals. All were given a verbal learning test assessing recall after 30 min, 1 week and 6 weeks.Results: In our study, the Left-TLE (L-TLE) group showed a statistically significant reduction in the performance at all assessment intervals from 30 min to 1 week compared to the Right-TLE and control groups regarding verbal learning memory test (VLMT) as well as for logical memory. The forgetting rates in the VLMT from 30 min to 1 week were not statistically significantly different between all 3 groups. The logical memory test results equally showed no statistically significant difference in the forgetting rates for the 3 groups between 30 min and 1 week.Conclusions and clinical implications: These results may support ongoing debates assuming the initial low performance in the memory of L-TLE patients to be directly related with left hippocampal-temporal tissue loss irrespective of epileptic activity. The discovery of the ALF phenomenon explains that standard memory tests are unable to detect memory loss in some patients who are experiencing a significant level of problems with forgetfulness in their daily lives.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectTemporal Lobe Epilepsyen_US
dc.subjectAmygdalohippocampectomyen_US
dc.subjectAccelerated Long-Term Forgettingen_US
dc.titleAccelerated long-term forgetting after amygdalohippocampectomy in temporal lobe epilepsyen_US
dc.typearticleen_US
dc.relation.ispartofJournal of Clinical Neuroscienceen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalıen_US
dc.authorid0000-0001-7566-1063en_US
dc.authorid0000-0003-3253-9222en_US
dc.identifier.volume72en_US
dc.identifier.startpage43en_US
dc.identifier.endpage49en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.jocn.2020.01.038en_US
dc.identifier.wosqualityQ4en_US
dc.identifier.scopusqualityQ2en_US


Bu öğenin dosyaları:

Thumbnail

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster