dc.contributor.author | Polat, Burcu | |
dc.contributor.author | Helvacı Yılmaz, Nesrin | |
dc.contributor.author | Mantar, Nagihan | |
dc.contributor.author | Çadırcı, Fadime | |
dc.contributor.author | Sitrava, Sevilay | |
dc.contributor.author | Ozmansur, Elif Nurdan | |
dc.contributor.author | Uzan, Mustafa | |
dc.contributor.author | Özkara, Çiğdem | |
dc.contributor.author | Hanoǧlu, Lütfü | |
dc.date.accessioned | 2020-04-16T09:53:32Z | |
dc.date.available | 2020-04-16T09:53:32Z | |
dc.date.issued | 2020 | en_US |
dc.identifier.citation | Polat, B., Helvacı Yılmaz, N., Mantar, N., Çadırcı, F., Sitrava, S., Ozmansur, E. N. ... Hanoǧlu, L. (2020). Accelerated long-term forgetting after amygdalohippocampectomy in temporal lobe epilepsy. Journal of Clinical Neuroscience, 72, 43-49. https://dx.doi.org/10.1016/j.jocn.2020.01.038 | en_US |
dc.identifier.issn | 0967-5868 | |
dc.identifier.issn | 1532-2653 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/5132 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.jocn.2020.01.038 | |
dc.description.abstract | Aim of the study: Temporal lobe epilepsy (TLE) has been associated with the phenomenon of accelerated long-term forgetting (ALF). In this study, we aimed to demonstrate the effect of surgery on the ALF phenomena thus contributing to potential explanation of the causal mechanism.Materials and methods: We evaluated 51 patients with TLE related to hippocampal sclerosis who had amygdalohippocampectomy and had remained seizure-free after surgery. A control group consisted of 24 healthy individuals. All were given a verbal learning test assessing recall after 30 min, 1 week and 6 weeks.Results: In our study, the Left-TLE (L-TLE) group showed a statistically significant reduction in the performance at all assessment intervals from 30 min to 1 week compared to the Right-TLE and control groups regarding verbal learning memory test (VLMT) as well as for logical memory. The forgetting rates in the VLMT from 30 min to 1 week were not statistically significantly different between all 3 groups. The logical memory test results equally showed no statistically significant difference in the forgetting rates for the 3 groups between 30 min and 1 week.Conclusions and clinical implications: These results may support ongoing debates assuming the initial low performance in the memory of L-TLE patients to be directly related with left hippocampal-temporal tissue loss irrespective of epileptic activity. The discovery of the ALF phenomenon explains that standard memory tests are unable to detect memory loss in some patients who are experiencing a significant level of problems with forgetfulness in their daily lives. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Temporal Lobe Epilepsy | en_US |
dc.subject | Amygdalohippocampectomy | en_US |
dc.subject | Accelerated Long-Term Forgetting | en_US |
dc.title | Accelerated long-term forgetting after amygdalohippocampectomy in temporal lobe epilepsy | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Journal of Clinical Neuroscience | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0001-7566-1063 | en_US |
dc.authorid | 0000-0003-3253-9222 | en_US |
dc.identifier.volume | 72 | en_US |
dc.identifier.startpage | 43 | en_US |
dc.identifier.endpage | 49 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1016/j.jocn.2020.01.038 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.scopusquality | Q2 | en_US |