Ara
Toplam kayıt 39, listelenen: 21-30
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in septic arthritis
(Sage Publications, 2015)
Is neutrophil-to-lymphocyte ratio high in patients with septic arthritis? Septic arthritis may lead to higher rates of morbidity or even mortality if not diagnosed on time. This study was planned to answer the question ...
Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue
(Spandidos Publications Ltd, 2018)
The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clinicians, exert toxic effects on human primary nucleus ...
The association between different molecular weights of hyaluronic acid and CHAD, HIF-1 alpha, COL2A1 expression in chondrocyte cultures
(Spandidos Publications Ltd, 2018)
The aim of the present study was to investigate the effects of three different formulations of hyaluronic acid (HA): Low molecular weight (MW) Sinovial One((R)), medium MW Viscoplus((R)) and high MW Durolane((R)), on ...
Are radio-contrast agents commonly used in discography toxic to the intact intervertebral disc tissue cells?
(Wiley, 2019)
In the literature, there have been no studies showing clear results on how radio-contrast pharmaceuticals would affect intact disc tissue cells. In this context, it was aimed to evaluate the effects of iopromide and gadoxetic ...
Are biological agents toxic to human chondrocytes and osteocytes?
(BioMed Central, 2015)
Purpose: The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Methods: Primary cell cultures obtained from gonarthrosis patients were divided ...
Safety of bioabsorbable implants in vitro
(BioMed Central, 2015)
Background: The aim of the present study was to investigate the safety of bioabsorbable plates and screws in humans. Methods: For this purpose, an implant system based on [poly(lactic-co-glycolic acids)(85:15)] was designed. ...
Is it possible to treat osteosarcoma using oligonucleotides confined into controlled release drug delivery systems?
(Bentham Science Publishers Ltd, 2017)
Purpose: The present study aimed to analyze the researches that are at the experimental phase concerning osteosarcoma treatment. The researches included drug delivery systems which allow controlled release and imbue small ...
Iopromide- and gadopentetic acid-derived preparates used in MR arthrography may be harmful to chondrocytes
(BMC, 2017)
Background: Magnetic resonance arthrography, a procedure through which contrast agents containing gadolinium and/or iopromide are administered intra-articularly, has become a useful tool in musculoskeletal diagnosis. ...
Assessing the negative impact of phenyl alkanoic acid derivative, a frequently prescribed drug for the suppression of pain and inflammation, on the differentiation and proliferation of chondrocytes
(BMC, 2016)
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to relieve pain and inflammation. These NSAIDs have also analgesic effects and can be administered via oral, injectable, and topical ...
Effect of naproxen on proliferation and differentiation of primary cell cultures isolated from human cartilage tissue
(Spandidos Publications Ltd, 2018)
Non-steroidal anti-inflammatory drugs (NSAIDs) that are applied through oral, injectable or topical routes have been widely used in painful and inflammatory musculoskeletal diseases. The current study aimed to determine ...