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Toplam kayıt 3, listelenen: 1-3
Cytokeratin 18 for chemotherapy efficacy in gastric cancer
(AME Publishing Company, 2015)
Cytokeratin 18 (CK18) is the major component of intermediate filaments in epithelial cells and released into the blood in either intact (M65) or caspase-cleaved forms (M30) during apoptotic and necrotic cell death. M30 and ...
A proteomic analysis of p53-independent induction of apoptosis by bortezomib in 4T1 breast cancer cell line
(Elsevier Science, 2015)
The 26S proteasome is a proteolytic enzyme found in both cytoplasm and nucleus. In this study, we examined the differential expression of proteasome inhibitor bortezomib-induced proteins in p53-deficient 4T1 cells. It was ...
Cytotoxic, antiproliferative and apoptotic effects of new benzimidazole derivatives on A549 lung carcinoma and C6 glioma cell lines
(Bentham Science Publishers, 2015)
Benzimidazole ring is a versatile structure which has been extensively utilized in medicinal chemistry. Since we are working on 1,2-disubstutited benzimidazoles, we have reported new antitumor active derivatives. As a ...