Ara
Toplam kayıt 57, listelenen: 21-30
Response to first-line chemotherapy regimen is associated with efficacy of immune checkpoint blockade therapies in patients with metastatic urothelial carcinoma
(Springer, 2022)
Background Atezolizumab (ATZ) has demonstrated antitumor activity in previous studies in patients with metastatic platinum-resistant urothelial carcinoma. However, the response rate of ATZ was modest. Therefore, finding ...
Real-life analysis of efficacy and safety of everolimus plus exemestane in hormone receptor-positive, human epidermal growth factor receptor-2-negative metastatic breast cancer patients: A Turkish Oncology Group (TOG) study
(Taylor & Francis Inc, 2022)
Purpose: This study evaluated the efficacy and safety of everolimus (EVE) plus exemestane (EXE) in hormone-receptor positive (HR+), human epidermal growth factor receptor-2-negative (HER2−) metastatic breast cancer (MBC) ...
Platelet to lymphocyte ratio is associated with tumor localization and outcomes in metastatic colorectal cancer
(Lippincott Williams & Wilkins, 2021)
The aim of this study was to investigate the predictive and prognostic value of PLR, and the relationship between PLR and tumor localization. A total of 229 patients with de-novo metastatic CRC were retrospectively analyzed. ...
Glass: Global lorlatinib for ALK(+) and ROS1(+) retrospective study: Real world data of 123 NSCLC patients
(Elsevier Ireland Ltd, 2020)
Lorlatinib is a third-generation tyrosine-kinases inhibitor (TKI) targeting ALK/ROS1 fusions. The FDA has approved lorlatinib for TKI-pretreated ALK(+) NSCLC, while its approval for ROS1( + ) is still pending. Here we ...
Prognostic significance of metastatic lymph node ratio in patients with pN3 gastric cancer who underwent curative gastrectom
(Karger, 2019)
Background: Lymph node involvement is an important prognostic factor in patients with gastric cancer. The aim of this study was to determine the prognostic significance of metastatic lymph node ratio (MLNR) and compare it ...
Pretreatment platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio as a predictor of pathological complete response to neoadjuvant chemotherapy in patients with breast cancer: Single center experience from Turkey
(Lippincott Williams and Wilkins, 2022)
The aim of this study was to investigate the predictive value of PLR and NLR as an indicator of pathological complete response (pCR) in patients with breast cancer after NACT. One hundred thirty-nine patients with early ...
Anti-Ri-associated paraneoplastic neurological syndrome: Initial symptom of breast cancer with HER2 overexpression and treatment by dual HER2 blockade
(SAGE Publications Ltd, 2019)
Paraneoplastic neurological syndrome is associated with anti-Ri antibodies, which are typically present with opsoclonus–myoclonus–ataxia. Human epidermal growth factor receptor 2 (HER2) overexpression is present in 15%–25% ...
Association and prognostic significance of the functional-1562C/T polymorphism in the promoter region of MMP-9 in Turkish patients with gastric cancer
(Springer, 2015)
Matrix metalloproteinases (MMPs) are a group of zinc-dependent peptidases that participate in matrix turnover in solid malignancies. The aim of this study was twofold. First, we sought to investigate under a case-control ...
Papilödem: Leptomeninjiyal metastazın önemli klinik işareti olabilir mi?
(Galenos Yayıncılık, 2020)
Amaç: Leptomeninjiyal metastaz (LM) tüm kanser tiplerinde izlenebilen nadir ancak kötü prognozlu bir klinik tablodur. Tanı, tedavi ve prognoz hastalığı yönetmekte önemli süreçlerdendir. Bu amaçla LM klinik ve laboratuvar ...
Prognostic impact of tumor lymphocytic infiltrates in patients with breast cancer undergoing neoadjuvant chemotherapy
(Zerbinis Publications, 2015)
Purpose: The presence of a pronounced tumor lymphocytic infiltrate (TLI) is deemed to reflect the presence of an immunoinflammatory response against the tumor and may thus have prognostic significance. We investigated the ...