WoS İndeksli Yayınlar Koleksiyonu by Institution Author "Akyel, Yasemin Kübra"

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Circadian dysfunction in adipose tissue: Chronotherapy in metabolic diseases

Civelek, Erkan; Öztürk Civelek, Dilek; Akyel, Yasemin Kübra; Kaleli Durman, Deniz; Okyar, Alper (MDPI, 2023)

Essential for survival and reproduction, the circadian timing system (CTS) regulates adaptation to cyclical changes such as the light/dark cycle, temperature change, and food availability. The regulation of energy homeostasis ...
Diurnal changes in capecitabine clock-controlled metabolism enzymes are responsible for its pharmacokinetics in male mice

Akyel, Yasemin Kübra; Öztürk Civelek, Dilek; Öztürk Seyhan, Narin; Gül, Şeref; Gazioğlu, Işıl; Pala Kara, Zeliha; Levi, Francis; Kavaklı, İbrahim Halil; Okyar, Alper (SAGE Publications Inc., 2023)

The circadian timing system controls absorption, distribution, metabolism, and elimination processes of drug pharmacokinetics over a 24-h period. Exposure of target tissues to the active form of the drug and cytotoxicity ...