Bölüm "İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı" WoS İndeksli Yayınlar Koleksiyonu için listeleme
Toplam kayıt 82, listelenen: 1-20
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Abnormal cross frequency coupling of brain electroencephalographic oscillations related to visual oddball task in parkinson's disease with mild cognitive impairment
(SAGE Publications Inc., 2023)Parkinson's disease (PD) is a movement disorder caused by degeneration in dopaminergic neurons. During the disease course, most of PD patients develop mild cognitive impairment (PDMCI) and dementia, especially affecting ... -
Active shrinkage protects neurons following axonal transection
(Elsevier Inc., 2023)Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ... -
Age-associated resilience against ischemic injury in mice exposed to transient middle cerebral artery occlusion
(Springer, 2023)Ischemic stroke is the leading cause of death and disability. Although stroke mainly affects aged individuals, animal research is mostly one on young rodents. Here, we examined the development of ischemic injury in young ... -
Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
(Elsevier B.V., 2022)Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ... -
The association between HbA1c levels, olfactory memory and cognition in normal, pre-diabetic and diabetic persons
(Bentham Science Publ Ltd, 2020)Background and Aim: Recent data have shown that olfactory dysfunction is strongly related to Alzheimer's Disease (AD) that is often preceded by olfactory deficits suggesting that olfactory dysfunction might represent an ... -
Building bridges through science
(Cell Press, 2017)Science is ideally suited to connect people from different cultures and thereby foster mutual understanding. To promote international life science collaboration, we have launched "The Science Bridge'' initiative. Our current ... -
Centralized healthcare database for ensuring better healthcare: Are we lagging behind?
(Professional Medical Publications, 2024)Database is an organized set of large information gathered and stored electronically to be retrieved whenever required. The systematically stored information can be ... -
Chemogenetic tools for causal cellular and neuronal biology
(American Physiological Society, 2018)Chemogenetic technologies enable selective pharmacological control of specific cell populations. An increasing number of approaches have been developed that modulate different signaling pathways. Selective pharmacological ... -
Clinical evaluation and resting state fMRI analysis of virtual reality based training in Parkinson's disease through a randomized controlled trial
(Nature Research, 2022)There are few studies investigating the short-term effects of Virtual Reality based Exergaming (EG) on motor and cognition simultaneously and pursue the brain functional activity changes after these interventions in patients ... -
A co-culture-based multiparametric imaging technique to dissect local H2O2 signals with targeted HyPer7
(MDPI, 2021)Multispectral live-cell imaging is an informative approach that permits detecting biological processes simultaneously in the spatial and temporal domain by exploiting spectrally distinct biosensors. However, the combination ... -
A comparative study of fixatives for axolotl blastema tissue
(Soc Chilena Anatomia, 2017)Regeneration is defined as tissue renewal and functional restoration process of the damaged parts of the body after an injury. Ambystoma mexicanum, commonly named the Axolotl, is one of the unique vertebrates, which has a ... -
Comparison of protein expression profile of limb regeneration between neotenic and metamorphic axolotl
(Elsevier, 2020)The axolotl (Ambystoma mexicanum) salamander, a urodele amphibian, has an exceptional regenerative capacity to fully restore an amputated limb throughout the life-long lasting neoteny. By contrast, when axolotls are ... -
Complexities of the chemogenetic toolkit: Differential mDAAO activation by D-amino substrates and subcellular targeting
(Elsevier Inc., 2021)A common approach to investigate oxidant-regulated intracellular pathways is to add exogenous H2O2 to living cells or tissues. However, the addition of H2O2 to the culture medium of cells or tissues approach does not ... -
Detailed tail proteomic analysis of axolotl (Ambystoma mexicanum) using an mRNA-seq reference database
(Wiley, 2017)Salamander axolotl has been emerging as an important model for stem cell research due to its powerful regenerative capacity. Several advantages, such as the high capability of advanced tissue, organ, and appendages ... -
Development of a chemogenetic approach to manipulate intracellular pH
(American Chemical Society, 2023)Chemogenetic Operation of iNTRacellular prOton Levels(pH-Control)is a novel substrate-based enzymatic method that enables precise spatiotemporalcontrol of ultralocal acidification in cultured cell lines and primaryneurons. ... -
A different view on the pathophysiology of Parkinson’s disease: A descendent neurochemical hypothesis?
(Wolters Kluwer, 2019)It has been already shown that Parkinson’s disease (PD) is characterized by a prominent degeneration in substantia nigra (SN)neurons. Growing evidence suggests that there is a latent period of PD associated with slight ...